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The Laryngoscope VC 2014 The American Laryngological, Rhinological and Otological Society, Inc. In Vivo Optical Imaging of Folate Receptor-b in Head and Neck Squamous Cell Carcinoma Joel Y. Sun, BA; Jiayin Shen, PhD; Joel Thibodeaux, MD; Gang Huang, PhD; Yiguang Wang, PhD; Jinming Gao, PhD; Philip S. Low, PhD; Dimiter S. Dimitrov, PhD; Baran D. Sumer, MD Objectives/Hypothesis: Folate receptor (FR) expression, although known to be elevated in many types of cancer and inflammatory cells, has

Transistor-like Ultra-pH-Sensitive Polymeric Nanoparticles Published as part of the Accounts of Chemical Research special issue “Nanomedicine and Beyond”. Qiang Feng, Jonathan Wilhelm, and Jinming Gao* Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, Texas 75390, United States CONSPECTUS: Electronic transistors have revolutionized the fields of micro- electronics, computers, and mobile devices. Their ability to

Contents lists available at ScienceDirect Journal of Controlled Release journal homepage: www.elsevier.com/locate/jconrel Synthetic nanovaccines for immunotherapy Min Luoa, Layla Z. Samandia, Zhaohui Wanga, Zhijian J. Chenb,c, Jinming Gaoa,⁎ a Department of Pharmacology, Simmons Comprehensive Cancer Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA b Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA c Howard

ARTICLES PUBLISHED ONLINE: 8 DECEMBER 2013 | DOI: 10.1038/NMAT3819 A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals Yiguang Wang1, Kejin Zhou1, Gang Huang1, Christopher Hensley2, Xiaonan Huang1, Xinpeng Ma1, Tian Zhao1, Baran D. Sumer3, Ralph J. DeBerardinis2 and Jinming Gao1* Stimuli-responsive nanomaterials are increasingly important in a variety of applications such as biosensing, molecular imaging, drug

NATURE BIOMEDICAL ENGINEERING 1, 0006 (2016) | DOI: 10.1038/s41551-016-0006 | www.nature.com/natbiomedeng 1 ARTICLES PUBLISHED: 19 DECEMBER 2016 | VOLUME: 1 | ARTICLE NUMBER: 0006 A transistor-like pH nanoprobe for tumour detection and image-guided surgery Tian Zhao1​†, Gang Huang1, Yang Li1, Shunchun Yang1, Saleh Ramezani2, Zhiqiang Lin1, Yiguang Wang1, Xinpeng Ma1, Zhiqun Zeng1, Min Luo1, Esther de Boer3, Xian-Jin Xie4, Joel Thibodeaux5, Rolf A. Brekken6, Xiankai Sun2, Baran D. Sumer7

A STING-activating nanovaccine for cancer immunotherapy Min Luo1†, Hua Wang2†, Zhaohui Wang1†, Haocheng Cai2, Zhigang Lu3, Yang Li1, Mingjian Du2, Gang Huang1, Chensu Wang1, Xiang Chen2, Matthew R. Porembka4, Jayanthi Lea5, Arthur E. Frankel6, Yang-Xin Fu7, Zhijian J. Chen2,8* and Jinming Gao1* The generation of tumour-specific T cells is critically important for cancer immunotherapy1,2. A major challenge in achieving a robust T-cell response is the spatiotemporal orchestration of antigen cross

1 Joseph Martin Ready Department of Biochemistry University of Texas Southwestern Medical Center 5323 Harry Hines Blvd. Dallas, TX 75390-9038 (214) 648-0313 joseph.ready@utsouthwestern.edu Employment 2012 – Professor, UT Southwestern 2009 – Director, Medicinal Chemistry Laboratory, UT Southwestern 2007 – 2012 Associate Professor, UT Southwestern 2007 – Chair, chemistry training track, UT Southwestern 2003 – 2007 Assistant Professor, UT Southwestern and

Postdoctoral Position in Neuroimaging A postdoctoral training position is available in the BioMedical Imaging Research Lab (BiMIR) led by Dr. Jiaen Liu in the Advanced Imaging Research Center (AIRC) at UT Southwestern Medical Center to develop advanced high resolution MRI methods for neuroimaging applications. BiMIR has several exciting projects related to novel MRI acquisition and reconstruction, ultrahigh-field MRI (≥7 T), quantitative MRI (T2, T2* and MT) for myelin and iron

December 26, 2016 Chen Lab Weekly Meeting Schedule Wednesday at 9 am (unless indicated otherwise), NA6.214 1/4/17 Chee-Kwee & Jueqi 1/19/17 (Thursday) Mingjian & Shuiqing (NA8.218) 1/24/17 (Tuesday) Junyao & Seoyun (NA8.218) 2/3/17 (Friday) Youtong & Fenghe 2/8/17 Nicole & Philip 2/15/17 Xiang G & Xiang C 2/24/17 (Friday) Ming & Hanze W 3/1/17 Conggang & Hua 3/8/17 Peiqing & Hui Y 3/15/17 Xiaojun & Junjiao 3/24/17 (Friday

Bu cc al B ru sh Gentra Puregene Handbook 06/201128 Protocol: DNA Purification from a Buccal Brush Using the Gentra Puregene Buccal Cell Kit This protocol is for purification of genomic DNA from 1 buccal brush using the Gentra Puregene Buccal Cell Kit. Things to do before starting � Preheat water baths to 55°C for use in step 3b and 65°C for use in steps 3a and 17 of the procedure. � Optional: Preheat water bath to 37°C for use in step 5 of the procedure. Procedure 1. To collect