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A drug approved to treat breast cancer patients with mutations in the BRCA1 or BRCA2 genes may also benefit people who have other genetic mutations.

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models.

Low-income seniors were seven times more likely to visit a food pantry in the year after becoming eligible for Medicare, resulting in improved food security, according to a new study from UT Southwestern.

For the third year in a row, UT Southwestern is ranked as the top health care institution globally by Nature Index for publishing high-quality research in all subjects and in the life sciences.

An enzyme called Fic, whose biochemical role was discovered at UT Southwestern more than a dozen years ago, appears to play a crucial part in guiding the cellular response to stress, a new study suggests.

For patients with estrogen receptor (ER)-positive breast cancer, development of the so-called Y537S mutation signals that their disease has taken an aggressive course and may become resistant to endocrine therapy.

While public attention has been focused on the million-plus Americans who have died from COVID-19 and the ongoing level of cases and hospitalizations, tens of millions of patients have developed life-altering symptoms that linger long after their COVID-19 infection clears.

Leveraging its broad expertise in biomedical informatics, data sciences, and clinical sciences, UT Southwestern Medical Center is aggressively expanding its involvement in clinical informatics, which aims to harness the power of big data to improve patient care and public health.

Over the first year of the COVID-19 pandemic, almost 30% of patients with obesity gained more than 5% of their body weight, and 1 in 7 gained more than 10%. While diet and exercise habits were factors, people with the highest levels of stress, anxiety, and depression reported the most weight gain.

A new imaging device at UT Southwestern is making complex aortic repairs safer for patients and operating room staff by dramatically reducing their exposure to radiation.