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More than two-thirds of 16-year-olds today have been through a traumatic event, such as the Central Texas flooding in July that killed over 130 people, including numerous children at summer camp.

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the surfaces of many cell types that generate their movement.

Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led by UT Southwestern Medical Center researchers shows.

UT Southwestern Medical Center is the No. 1 hospital in Dallas-Fort Worth for the ninth consecutive year and ranks among the nation’s top hospitals for care in 12 specialties – the most of any hospital in Texas, according to U.S. News & World Report’s annual Best Hospitals list released today.

By using a genetic technique they developed that forces cells to rid themselves of mitochondria, UT Southwestern Medical Center researchers are gaining new insights into the function of these critical organelles.

A single, high dose of radiation delivered before other treatments could completely eradicate tumors in most women with early-stage, operable hormone-positive breast cancer, according to a study led by UT Southwestern Medical Center researchers.

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts (apCAFs) that appear to support the survival and growth of malignant tumors. Their findings, reported in Cancer Cell, could one day lead to new therapies for notoriously hard-to-treat cancers, including pancreatic cancer and advanced colorectal cancer (CRC) that has spread throughout the abdomen, known as peritoneal metastasis.

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets – a phenomenon that’s pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows.

New research has uncovered a surprising role for so-called “jumping” genes that have traditionally been considered a source of genetic mutations responsible for a number of human diseases.

Scientists at UTSW have developed a technology that shuttles nanoparticles carrying gene editing and protein replacement tools to the specific tissues where they're needed.