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Silac Quantitation Introduction Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) is a powerful technique for comparing protein (and peptide) amounts between two or three conditions. Developed in the lab of Matthias Mann it is one of the most widely used labeled quantitation methods in p…

PTM Identification Introduction The presence or absence of post-translational modifications (PTMs), such as phosphorylation, on a protein are often as interesting as the presence of absence of the protein itself. The PTM ID service offers identification of PTMs on a protein from a purified protein or…

Cutting Gels Introduction Many proteomics samples are well suited for SDS-PAGE, including protein identification and PTM identification. We recognize that a gel approach may not be compatible with all samples, so please contact us if you have concerns about running your sample into a gel. We require …

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Charging Policy What is our policy for charging users? The Proteomics Core has a simple charging policy: No samples will be prepared or run until the information has been entered into our sample submission site. We charge for every sample run , regardless of whether an expected result is obtained. Th…

TMT Quantitation Introduction Tandem Mass Tag (TMT) technology is a powerful technique for comparing protein (and peptide) amounts between six to eighteen conditions. This technique involves labeling samples after digestion, meaning this technique can be used on in vivo samples, unlike SILAC. TMT or …

The archive contains composites of the alumni of the UT Southwestern Radiology Department.

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The McDermott Center Human Genetics Clinical Lab is dedicated to help accelerate the pace of human genetic research by providing skilled assistance with collecting and storing biologic specimens.