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A compound synthesized by a team led by UT Southwestern scientists kills a range of hard-to-treat cancer types by targeting a previously unexploited vulnerability, a new study reports.

UT Southwestern researchers Zhijian “James” Chen, Ph.D., and Sihan Wu, Ph.D., are part of a team that has been awarded a Cancer Grand Challenges grant, a unique award that aims to solve some of cancer’s toughest problems by bringing together global teams with diverse areas of expertise.

Fifteen scientists in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern received more than $17 million in research funds in the latest round of grants awarded by the Cancer Prevention and Research Institute of Texas (CPRIT).

A multicenter study performed by a large international consortium that includes UT Southwestern has outlined a set of risk factors and outcomes for patients with autoimmune hepatitis (AIH) that recurs after liver transplantation.

Hip and knee replacements, sports injuries, trauma. That’s typically what comes to mind when one thinks of orthopedic surgery, not diabetes.

Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study led by UT Southwestern researchers suggests.

A generous $25 million commitment from the Once Upon a Time Foundation will create the Raynor Cerebellum Project at UT Southwestern Medical Center (RCP-UTSW) to investigate diseases associated with cerebellum dysfunction, with the goal of discovering how to preserve and restore lost brain function.

UT Southwestern researchers have discovered a molecular pathway that allows cells to sense when their lipid supplies become depleted, prompting a flurry of activity that prevents starvation. The findings, reported in Nature, might someday lead to new ways to combat metabolic disorders and a variety of other health conditions.

A team led by UT Southwestern Medical Center cardiologist Ambarish Pandey, M.D., was awarded the grand prize in the American Heart Association Heart Failure Data Challenge hosted by the American Heart Association and the Association of Black Cardiologists.

Reuben Arasaratnam, M.D., M.P.H., Assistant Professor of Internal Medicine at UT Southwestern, has been named one of 11 2022 Scholars in Diagnostic Excellence by the National Academy of Medicine (NAM).