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Simulation reveals new mechanism for membrane fusion: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/april-new-mechanism-for-membrane-fusion.html

– An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.

UTSW Research: Improved bladder cancer detection, tracking gamma waves, and more: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/may-improved-bladder-cancer-detection.html

Studies analyze blue light cystoscopy, irregularities in brain activity, the origins of abnormal bone formations, and HIV transcription.

ER patient portal usage increasing, study shows: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/may-patient-portal-er-visits.html

More people are using online patient portals to view their information while in the emergency room, but access is challenging for members of medically underserved communities and the elderly, UT Southwestern Medical Center researchers and national colleagues found in a new study.

Essential tremor triples dementia risk, UTSW study shows: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/april-tremor-triples-dementia-risk.html

Patients with a common movement disorder known as essential tremor (ET) developed dementia at three times the rate of similarly aged people in the general population, a study led by UT Southwestern Medical Center researchers shows.

Combined therapy makes headway for liver cancer: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/may-combined-therapy-live-cancer.html

A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without compromising their safety, according to results of a phase two clinical trial conducted by UT Southwestern Medical Center.

Machine learning sheds light on gene transcription : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/may-machine-learning-gene-transcription.html

A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters – regions of DNA that initiate the process by which genes produce proteins.

Cancer cell–immune cell interactions predict immunotherapy response: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/april-cancer-cell-immune-cell-interactions.html

By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with breast cancer will respond to immunotherapies.

UT Southwestern finds genetic clues to complex infections: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/feb-genetic-clues-to-complex-infections.html

Treating complex bacterial infections with customized therapies tailored to the infection and the patient is closer to reality, thanks to researchers at UT Southwestern Medical Center.

UTSW study identifies RNA molecule that regulates cellular aging : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/july-rna-molecule-cellular-aging.html

A team led by UT Southwestern Medical Center researchers has discovered a new way that cells regulate senescence, an irreversible end to cell division. The findings, published in Cell, could one day lead to new interventions for a variety of conditions associated with aging, including neurodegenerative and cardiovascular diseases, diabetes, and cancer, as well as new therapies for a collection of diseases known as ribosomopathies.

E-scooter injuries can come at a cost to the public: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/jan-e-scooter-accident-injuries.html

Electric scooters carry a significant risk of orthopedic injuries and associated costs for medical care, which can create a financial burden for the public, according to a study by UT Southwestern Medical Center researchers.