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As they grow, solid tumors surround themselves with a thick, hard-to-penetrate wall of molecular defenses. Getting drugs past that barricade is notoriously difficult.

Children’s Health significantly expands access to pediatric behavioral health services

For three decades, scientists have debated the underlying cause of Gulf War illness (GWI), a collection of unexplained and chronic symptoms affecting veterans of the Persian Gulf War.

Using UT Southwestern’s Cryo-Electron Microscopy Facility, researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation.

A collaborative study from UT Southwestern scientists has identified a new function for a protein called TAO2 that appears to be key to inhibiting replication of the influenza virus, which sickens millions of individuals worldwide each year and kills hundreds of thousands.

Magnetic resonance imaging (MRI) can reliably establish measurements for anterior cruciate ligament (ACL) “footprints” that are critical to the placement of grafts for reconstruction surgery, UT Southwestern researchers report.

Today, the North Texas FWC Organizing Committee announced that UT Southwestern Medical Center has been named an Official World Cup 2026™ Dallas Host City Supporter, joining a select group of leading organizations welcoming the world’s largest sporting event to North Texas.

A set of interacting molecules in immune cells of the gut is responsible preventing the inflammation seen in inflammatory bowel diseases (IBD), UT Southwestern researchers report in a new study.

A new study by the Kidney Cancer Program (KCP) at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center shows that highly focused radiation to isolated metastases that progress despite drug therapy can prolong drug use in kidney cancer patients, saving the few other drugs for treating kidney cancer for future use.

The most common bacterial infection to occur after revision shoulder arthroplasty surgery can be diagnosed more accurately by considering how quickly samples of the microbe grow in hospital labs and the level of bacteria that grows, a study partly performed at UT Southwestern shows.