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A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets – a phenomenon that’s pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows.

A single, high dose of radiation delivered before other treatments could completely eradicate tumors in most women with early-stage, operable hormone-positive breast cancer, according to a study led by UT Southwestern Medical Center researchers.

Researchers have identified factors associated with survival for patients initially diagnosed with metastatic breast cancer who were seen at UT Southwestern Medical Center and its affiliated sites.

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts (apCAFs) that appear to support the survival and growth of malignant tumors. Their findings, reported in Cancer Cell, could one day lead to new therapies for notoriously hard-to-treat cancers, including pancreatic cancer and advanced colorectal cancer (CRC) that has spread throughout the abdomen, known as peritoneal metastasis.

Dysfunctional mitochondria, organelles that serve as cellular power generators, appear to cause the symptoms of Gulf War illness (GWI) among tens of thousands of veterans of the Persian Gulf War, UT Southwestern Medical Center scientists confirmed in a new study.

Antibodies that target specific tuberculosis (TB) proteins are effective at inhibiting the bacteria that cause TB, the infectious disease that claims the most lives worldwide, a study led by UT Southwestern Medical Center researchers found.

The COVID-19 pandemic not only disrupted children’s education, recreation, and social lives, it also increased the prevalence of obesity in the U.S. pediatric population by roughly 1 million youngsters, according to a study led by UT Southwestern Medical Center researchers.

More than two-thirds of 16-year-olds today have been through a traumatic event, such as the Central Texas flooding in July that killed over 130 people, including numerous children at summer camp.

Two UT Southwestern Medical Center scientists – Zhijian “James” Chen, Ph.D., Professor of Molecular Biology and Director of the Center for Inflammation Research, and Michael Rosen, Ph.D., Chair and Professor of Biophysics – have been selected as 2025 Citation Laureates in recognition of work deemed by Clarivate to be of the highest impact.

Being younger doesn’t protect against the dangers of COVID-19 if you are overweight, according to a new study from UT Southwestern.