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UTSW researchers discover new drug target for inflammatory bowel disease: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-researchers-discover-new-drug.html

A set of interacting molecules in immune cells of the gut is responsible preventing the inflammation seen in inflammatory bowel diseases (IBD), UT Southwestern researchers report in a new study.

UT Southwestern geneticists identify new mechanism for nonalcoholic fatty liver disease absent obesity: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-nonalcoholic-fatty-liver-disease.html

Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.

New Intracept ablation proves effective for quelling low back pain: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-intracept-low-back-pain.html

UT Southwestern Spine Center is now offering a minimally invasive ablation procedure to provide relief for low back pain caused by traumatic injury or degeneration of the vertebral endplates.

Clinical trial shows stereotactic radiation extends systemic therapy and slows kidney cancer progression : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/stereotactic-radiation-extends-systemic-therapy.html

A new study by the Kidney Cancer Program (KCP) at UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center shows that highly focused radiation to isolated metastases that progress despite drug therapy can prolong drug use in kidney cancer patients, saving the few other drugs for treating kidney cancer for future use.

UT Southwestern designated one of 12 elite Nutrition Obesity Research Centers in the nation: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-nutrition-obesity-research-center.html

UT Southwestern Medical Center has been selected to be one of 12 NIH Nutrition Obesity Research Centers in the nation – and the only one in Texas – to investigate the causes, prevention, and treatment options for obesity, a chronic disease affecting more than 40% of the U.S. population with medical costs nearing $175 billion.

Shape-shifting fat cells fuel breast cancer growth: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-shape-shifting-fat-cells.html

Fat cells, or adipocytes, that grow in close proximity to breast cancers can shift into other cell types that promote tumor growth, a new study by UT Southwestern researchers suggests.

UT Southwestern opens first academic medical center campus for southern Dallas County: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/september-first-academic-medical-center-campus.html

More than 1,000 residents, business owners, and regional leaders gathered Saturday at the community celebration for the opening of UT Southwestern Medical Center at RedBird, the largest of its regional campuses and the first to bring academic medicine to the booming southern Dallas region.

Gene therapy corrects mutation responsible for common heart condition, research shows: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/december-gene-therapy-in-human-cells.html

Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.

UTSW Research: Improved bladder cancer detection, tracking gamma waves, and more: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/may-improved-bladder-cancer-detection.html

Studies analyze blue light cystoscopy, irregularities in brain activity, the origins of abnormal bone formations, and HIV transcription.

Simulation reveals new mechanism for membrane fusion: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/april-new-mechanism-for-membrane-fusion.html

– An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.