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Researchers at UT Southwestern Medical Center have linked blindness in animal models to a brain-wide cellular stress response that’s a common risk factor for dementia. Their findings, published in Nature Communications, could help explain the connection between vision or hearing loss and dementia.

Multidrug resistance in cancer can be overcome by combining a drug that blocks a key enzyme with another anticancer drug, according to a study in preclinical models led by researchers at UT Southwestern Medical Center. The findings, published in Science Advances, could have implications for patients with certain cancers that have KRAS-G12C mutations after resistance to drug therapy develops.

Using a novel method that gives a readout of which proteins are in specific locations within cells, UT Southwestern Medical Center researchers have identified a protein that plays a key role in cell adhesion and movement.

Researchers at UT Southwestern Medical Center have discovered sex-specific differences in how fat accumulates in muscle and bone, uncovering patterns that could inform new approaches to treating age-related diseases.

DNA that ends up where it doesn’t belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate.

A drug approved for diabetes has now been shown to also help patients with diabetes lose on average 10 percent of their body weight, UT Southwestern reports in a landmark international study.

UT Southwestern Medical Center is one of 13 inaugural organizations joining a newly launched partner network of The National Academies’ Action Collaborative on Preventing Sexual Harassment in Higher Education to support evidence-based policies and practices for preventing sexual harassment.

The importance of increasing the number of Black male doctors in the United States will be the subject of a virtual panel discussion at UT Southwestern in advance of the release of a documentary on the issue.

A set of biomarkers not traditionally associated with cell fate can accurately predict how genetically identical cells behave differently under stress, according to a UT Southwestern study.

The Centers for Medicare & Medicaid Services (CMS) announced that the Southwestern Health Resources Accountable Care Network (SWHR) saved more than $52 million in 2019.