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Former college athletes with a history of concussions were more likely to perceive themselves as cognitively impaired later in life if they had mood disorders such as depression and anxiety – even when testing showed no such decline in mental acuity, a study from UT Southwestern Medical Center researchers has found.

UT Southwestern Medical Center and InterAct Therapeutics have announced an exclusive licensing agreement to develop and commercialize a groundbreaking computational platform and gene therapy pipeline targeting cancer metastasis.

A team led by UT Southwestern scientists has discovered a mechanism that promotes metastasis in pancreatic, breast, and potentially other cancers along with a new druggable therapeutic target based on this mechanism to block metastases.

As a young man in his mid-20s, Jorge Gómez was one of thousands of Cuban citizens who fled communism and the island country on a raft in 1994. He would spend 11 months living in a tent city at Guantanamo Bay before being granted asylum in the U.S., where he overcame numerous obstacles to build a better life as an engineer and father of four boys in Carrollton, Texas.

Jiang He, M.D., Ph.D., Professor and Chair Designate of Epidemiology in the Peter O’Donnell Jr. School of Public Health at UT Southwestern Medical Center, is a 2024 recipient of the American Heart Association’s (AHA) highest commendation, the Distinguished Scientist award.

Despite the convenience of at-home screening tests for early detection of colorectal cancer (CRC), a study led by UT Southwestern Medical Center researchers examining more than a decade of patient data found that about 10% of the tests could not be processed, mostly due to patient error.

Using a powerful microscopy technique, a team led by researchers at UT Southwestern Medical Center has gained insights into how the body uses vitamin K, an essential nutrient that plays a pivotal role in blood clotting and other physiological functions.

KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT Southwestern Medical Center researchers suggests that different KRAS mutation types can variously impact how cancer cells interact with immune cells, significantly affecting the malignant cells’ behavior.

Disruptions in patterns of daily activity and rest may provide early clues to heightened dementia risk, a study co-led by a UT Southwestern Medical Center scientist found.

An experimental pill called enlicitide slashed levels of low-density lipoprotein (LDL) cholesterol, commonly known as “bad” cholesterol, by up to 60%, a new phase three clinical trial published in The New England Journal of Medicine showed.