Search

Complications after an amputation left Scott Bryson, a 50-year-old father of three, unable to walk. But in June 2023, he took his first steps in nearly a decade after receiving a revolutionary surgical procedure at UT Southwestern Medical Center.

A UT Southwestern Medical Center quality improvement team led a large-scale, multispecialty project in partnership with the Parkland Center of Innovation and Value to help patients with implantable cardioverter defibrillators (ICDs) better understand their devices and make choices about their care.

UT Southwestern Medical Center researchers have identified two distinct populations of cells known as antigen-presenting cancer-associated fibroblasts (apCAFs) that appear to support the survival and growth of malignant tumors. Their findings, reported in Cancer Cell, could one day lead to new therapies for notoriously hard-to-treat cancers, including pancreatic cancer and advanced colorectal cancer (CRC) that has spread throughout the abdomen, known as peritoneal metastasis.

A preclinical model developed at UT Southwestern Medical Center that recapitulates a rare infant-onset form of diabetes suggests the condition stems from gradual damage to the pancreas through misregulation of a molecular pathway called the unfolded protein response (UPR).

A gene-editing delivery system developed by UT Southwestern Medical Center researchers simultaneously targeted the liver and lungs of a preclinical model of a rare genetic disease known as alpha-1 antitrypsin deficiency (AATD), significantly improving symptoms for months after a single treatment, a new study shows.

UT Southwestern Medical Center has earned The Joint Commission’s Gold Seal of Approval® as a UT that represents the highest standard in cardiovascular care.

Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study.

An experimental treatment for depression that triggers seizures with magnets significantly improved mental health in patients without some cognitive effects associated with electroconvulsive therapy (ECT), a clinical trial led by UT Southwestern Medical Center researchers showed.

Three of the leading chatbots can provide basic information about endometriosis, a painful gynecologic condition that affects as many as 1 in 10 women, but their responses are not as comprehensive as the guidance from health care providers, according to a study by UT Southwestern Medical Center researchers.

Patients with cutaneous lupus erythematosus (CLE), an autoimmune disease that causes skin inflammation, have a higher risk for atherosclerotic cardiovascular disease (ASCVD), or hardening of the arteries, UT Southwestern Medical Center researchers found.