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Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.

Combining a common chemotherapy drug with an experimental nanotechnology allowed the drug to cross the blood-brain barrier and increased the survival rate in a mouse model of glioblastoma up to 50%, a team led by researchers from UT Southwestern Medical Center and UT Dallas found.

A clinical trial led by UT Southwestern Medical Center researchers demonstrates that providing healthy food directly to patients recovering from heart failure is feasible and well accepted – and could improve quality of life – helping build a foundation for larger studies exploring food as a component of medical care.

Everyone experiences stress from time to time. And while brief bouts can be a good thing, prolonged or chronic stress can have negative effects on your overall health.

Pelvic floor disorders (PFDs), which occur when women’s pelvic floor muscles are weakened or injured, significantly affect quality of life and require surgery for hundreds of thousands in the U.S. each year. Now a study led by UT Southwestern Medical Center researchers has found a noninvasive test that could identify women at risk for these conditions and improve treatment.

A study by UT Southwestern researchers has identified three factors that increase the risk that bunion surgery will fail to fix this painful foot condition.

Hepatocellular carcinoma (HCC), the most common type of liver cancer, can place a significant financial burden on patients, according to an analysis led by a researcher at UT Southwestern Medical Center.

– A widely used fracture risk calculator may help guide surgical decisions to treat patients with an endocrine disorder called primary hyperparathyroidism (PHPT) that causes progressive bone loss, according to a study led by UT Southwestern Medical Center researchers.

Complications after an amputation left Scott Bryson, a 50-year-old father of three, unable to walk. But in June 2023, he took his first steps in nearly a decade after receiving a revolutionary surgical procedure at UT Southwestern Medical Center.

Three of the leading chatbots can provide basic information about endometriosis, a painful gynecologic condition that affects as many as 1 in 10 women, but their responses are not as comprehensive as the guidance from health care providers, according to a study by UT Southwestern Medical Center researchers.