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An experimental antibody treatment that binds to a protein known as PCDH7 shrank tumors in preclinical models of non-small cell lung cancer (NSCLC), even those resistant to a targeted therapy, a study led by UT Southwestern Medical Center researchers showed.

An RNA-modifying enzyme linked to cancer and neurological disorders selects its targets by recognizing specific RNA shapes and sequences, according to a study by UT Southwestern Medical Center researchers.

When heart cells burn fat without normal metabolic controls, they can deplete a lipid needed to keep mitochondria functioning properly, according to a study by UT Southwestern Medical Center researchers.

A metabolic byproduct formed when gut bacteria break down dietary fiber appears to protect against dangerous fungal infections common in immunocompromised patients, a study led by UT Southwestern Medical Center researchers shows.

Branchlike structures called dendrites that extend from neurons appear to make their own “computations” independently of the cell body, helping individual brain cells store memories of the past, respond to the present, and anticipate the future, a study led by UT Southwestern Medical Center researchers suggests.

A UT Southwestern study is challenging concerns that a federal health policy enacted in 2012 to reduce hospital readmissions leaves patients more vulnerable.

Traditional cardiovascular risk factors, such as blood pressure, cholesterol levels, diabetes, and smoking status, are at least as valuable in predicting who will develop coronary heart disease as a sophisticated genetic test that surveys millions of different points in DNA.

The bacteria that cause the deadly lung disease tuberculosis appear to facilitate their own spread by producing a molecule that triggers cough.

Patients who received Mohs surgery to treat the most serious form of skin cancer, melanoma, reported a 95 percent long-term satisfaction rate with their results.

UT Southwestern Medical Center is expanding its neurological surgery program to Texas Health Presbyterian Hospital Dallas.