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Delivering genetic material tagged with a cellular “ZIP code” prompted cells to secrete proteins or drugs into the bloodstream that successfully treated psoriasis and cancer in mouse models, UT Southwestern Medical Center scientists report in a new study.

A protein called torsinA plays a key role in the early development of neurons, determining where nuclear pores are placed in the membrane that encloses the nucleus of nerve cells, a study led by UT Southwestern Medical Center researchers shows.

Zhijian “James” Chen, Ph.D., Professor of Molecular Biology and Director of the Center for Inflammation Research at UT Southwestern Medical Center, has been awarded the Albert Lasker Basic Medical Research Award for his discovery of the cGAS enzyme, which senses invading pathogens and triggers the body’s innate immune system.

Researchers have long known that outcomes for alcohol-associated liver disease (ALD) aren’t equal among all races and ethnicities in the U.S., but differences among these groups have been less clear.

UT Southwestern Medical Center stem cell and developmental biologists and colleagues have developed a method to produce bovine blastoids, a crucial step in replicating embryo formation in the lab that could lead to the development of new reproductive technologies for cattle breeding.

A new type of developmental disability caused by mutations in a gene known as CBX1 has been discovered by a UT Southwestern Medical Center researcher and his colleagues. The findings, reported in Genetics in Medicine, offer insight into the role this gene plays in development and could eventually lead to therapies for a range of related disorders.

Slipping on ice or tripping over a curb can result in broken bones or more serious injuries. To avoid taking an unexpected tumble, it’s important to be aware of your surroundings and watch where you’re walking, a UT Southwestern Medical Center orthopedist advises.

A multifaceted, team-based care strategy significantly reduced blood pressure (BP) in low-income patients with uncontrolled hypertension, according to a study led by researchers at UT Southwestern Medical Center.

Patients can die if they take certain previously prescribed beta-blockers during a hematopoietic cell transplant due to suppressed signals from nerves that promote bone marrow regeneration.

Stem cell biologist Sean J. Morrison, Ph.D., has been elected by his peers as an associate member of the European Molecular Biology Organization (EMBO).