Awards for June 2017

Federal Awards

Arnold, Susan, Duke Univ./NIH, Pharmacokinetics of Anti-Epileptic Drugs in Obese Children, $4,000; Beutler, Bruce (Fellow E. Turer), NIH, Forward Genetic Analysis of Intestinal Homeostasis, $143,961; Bezprozvanny, Ilya, NIH, Presenilins and Neuronal Calcium Dyshomeostasis, $459,113; Boothman, David, NIH, Tumor-Selective Use of PARP Inhibitors Against NQO1+ Non-Small Cell Lung Cancer, $410,854; Boothman, David, NIH, RPRD1B/Kub5/Hera, an RNA Pol II Determinant that Controls PARPi & IR Sensitivity, $370,575; Borek, Dominika, Georgia State Univ./NIH, Therapeutics Targeting Filoviral Interferon-Antagonist, $64,625; Brown, Sherwood, NIH, Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders, $661,620;

Burma, Sandeep, NASA, Mechanistic Analysis of Particle Radiation-Induced Carcinogenesis Using Validated Mouse Glioma Models, $437,221; Burstein, Ezra, NIH, Regulation of Copper Homeostasis by COMMD Proteins, $435,034; Burstein, Ezra, NIH, UT Gastroenterology/Hepatology Research Training Program, $277,948; Burstein, Ezra (Fellow A. Singla), NIH, Altered Endosomal Protein Sorting in the Pathogenesis of Hepatocellular Carcinoma, $124,040; Chook, Yuh Min, Univ. of Pa./NIH, Splicing and Nuclear Transport of Influenza Virus mRNA, $129,600; Cobb, Melanie, NIH, Cell and Molecular Biology Training Grant, $435,059; Corbin, Ian, NIH, Image Guided LDL Nanomedicine, $370,575;

Diamond, Marc, NIH, Development of Novel Therapeutic Anti-Tau Antibodies, $654,953; Diamond, Marc, Washington Univ. St. Louis/NIH, Mechanism of Modulation of Huntingtin Exon 1 Aggregation by Profilin, $156,780; Elmquist, Joel, NIH, Leptin and Insulin Signaling in SF1 Neurons and Energy Homeostasis, $333,900; Elmquist, Joel (Fellow L. Jia), NIH, Role of Hepatocyte TLR4 in Alcohol-induced Steatohepatitis and Insulin Resistance, $149,472; Fontoura, Beatriz, Univ. of Pa./NIH, Splicing and Nuclear Transport of Influenza Virus mRNA, $129,600; Fu, Yang-Xin, NIH, Role of Id2 in Gut Innate Lymphoid Cells, $352,350; Gao, Jinming, NIH, Nanoprobe-Enabled Delineation of Tumor Margins for Improved Surgical Therapy, $370,575;

Gardner, Lisa (Fellow A. Moehlman), Natl. Science Fdn., Graduate Research Fellowship Program, $46,000; Gardner, Lisa (Fellow A. Rice), Natl. Science Fdn., Graduate Research Fellowship Program, $46,000; Gardner, Lisa (Fellow M. Merriman), Natl. Science Fdn., Graduate Research Fellowship Program, $46,000; Gardner, Lisa (Fellow S. Elkassih), Natl. Science Fdn., Graduate Research Fellowship Program, $46,000; Gazdar, Adi, Sloan-Kettering Inst./NIH, Small Cell Lung Cancer Consortium Coordinating Center, $165,109; Goldberg, Mark, NIH, Network of Excellence in Neuroscience Clinical Trial, $318,000; Graff, Jonathan (Fellow Y. Jiang), NIH, Molecular Regulation of Adipose Tissue Development, Homeostasis, and Expansion, $102,876;

Hibbs, Ryan, NIH, Structural Studies of Heteromeric Nicotinic Acetylcholine Receptors, $364,500; Hooper, Lora, NIH, Bacterial Regulation of Intestinal Antimicrobial Defense, $345,825; Jaqaman, Khuloud, NIH, Mechanisms and Functional Consequences of Receptor Organization at Membranes, $397,121; Jiang, Youxing, NIH, Structural Mechanisms of Ion Selectivity and Gating in Tetrameric Cation Channels, $315,900; Johnson, Mark, Univ. of Miami/NIH, Mechanisms of Early Recurrence in Intracranial Atherosclerotic Disease (MyRIAD), $4,257; Kahn, Jeffrey, NIH, Innate Immune Activation by Respiratory Syncytial Virus, $202,500;

Kapadia, Vishal, NIH, Low Versus High Transitional Oxygen Saturation Targets for Preterm Resuscitation, $167,400; Karp, David, Benaroya Research Inst./NIH, CALIBRATE – Rituximab Plus Cyclophosphamide Followed by Belimumab, $5,989; Kerwin, Diana, UCSF/NIH, The Frontotemporal Lobar Degeneration Clinical Research Consortium, $36,744; Le, Lu, Dept. of Defense, Defining Molecular and Developmental Pathogenesis of Schwann Cell Tumors to Identify Therapeutic Targets, $283,500; Lee, Simon, NIH, Care Coordination for Complex Cancer Survivors in an Integrated Safety-Net System, $458,496; Liu, Chen, NIH, Hypothalamic Serotonin Receptors and Olanzapine-induced Metabolic Syndrome, $405,000;

Mineo, Chieko, NIH, Endothelial SR-BI and Metabolic Health, $405,000; Mishra, Prashant, Dept. of Defense, Engineering a Minimal Competency Machinery for Mitochondria, $324,000; Monson, Nancy, NIH, Immune Profiling of Encephalitis, $202,501; Munshi, Nikhil, NIH, Defining Process Control Parameters for Cardiac Reprogramming, $81,000; Nugent, Alan, Peca Labs/NIH, Novel Synthetic Vascular Graft Capable of Minimally Invasive Controlled Expansion to Match Somatic Growth in Neonatal and Pediatric Patients, $66,471; Powell, Craig, NIH, Novel Genetic Models of Autism, $627,293; Raskin, Philip, Benaroya Research Inst./NIH, EXTEND – Preserving Beta-Cell Function with Tocilizumab in New Onset Type 1 Diabetes, $10,739;

Ready, Joseph, Georgia State Univ./NIH, Therapeutics Targeting Filoviral Interferon-Antogonist and Replication Functions, $362,556; Satterthwaite, Anne, NIH, PIK3IP1 in B Cell Development and Function, $202,500; Scherer, Philipp, Yale Univ./NIH, Project 3: Impact of the FGF21-Adiponectin-Ceramide Axis on Healthspan, $300,348; Sherry, Dean, NIH, Metabolism in the Heart by NMR, $397,500; Takahashi, Joseph, NIH, Transcriptional Architecture and Chromatin Landscape of Circadian Clocks in Aging, $278,250; Tamminga, Carol, NIH, Basic Science Training Program in the Neurobiology of Mental Illness, $292,468;

Trivedi, Madhukar, NIH, Clinical Trials Network: The Texas Node, $771,469; Van Buren, Peter, NIH, Mechanisms of Increased Ambulatory Blood Pressure in Intradialytic Hypertension, $159,840; Vongpatanasin, Wanpen, NIH, Preventing Hypertension and Sympathetic Overactivation by Targeting Phosphate, $792,454; Wang, David, NIH, Hedgehog Signaling in the Development of Barrett’s Esophagus, $280,825; Wang, Zhao, NIH, Role of the Xbp1s/GFAT1 Axis in Pathological Cardiac Remodeling, $405,000;

Word, Ann, NIH, Mechanisms of Prostaglandin-induced Cervical Ripening in Humans, $336,150; Wu, Jiang, NIH, Role of Brg1 in Activity-Induced Neuronal Gene Expression and Synaptic Plasticity, $352,407; Yin, Helen, NIH, Mechanisms of Disease & Translational Science, $135,268; Zhang, Chun-Li, NIH, Chemical Reprogramming of Traumatic Brain Injury, $354,375; Zhu, Hao, NIH, Enhancing Mammalian Liver Repair and Regeneration, $364,500; Zinn, Andrew, NIH, Medical Scientist Training Program at UTSW, $917,600.

Nonfederal Awards

Ahmad, Zahid, American Heart Assoc., Statin-Associated Muscle Symptoms: In Vitro and In Vivo Studies of Mitochondrial Function, $75,000; Bai, Xiaochen, CPRIT, Recruitment of First-Time, Tenure-Track Faculty Member, $652,231; Banaszynski, Laura, Neuroendocrine Tumor Research Fdn., The Role of ATRX/DAXX/H3.3 Chromatin Regulation in Pancreatic Neuroendocrine Tumors, $150,000; Brugarolas, James, CPRIT, Targeting the undrugable: First-In-Class Inhibitor of HIF-2 Transcription, $299,804; Castrillon, Diego, CPRIT, Novel Tumorigenic Mechanisms of LKB1 Tumor Suppressor in Endometrial and Cervical Cancer, $297,102; Garg, Abhimanyu, Jain Fdn. Inc., Mechanisms of Muscle Steatosis in Dysferlinopathy: Relationship to Interaction of Dysferlin and PTRF, $100,000;

Gerber, David, CPRIT, Patient Navigation for Lung Cancer Screening in Urban Safety-Net System, $490,631; German, Dwight, Michael J. Fox Fdn., Blood Biomarker for Parkinson’s Disease, $71,000; Hill, Joseph (Fellow J. Savla), American College of Cardiology, Role of Mechanical Unloading after LVAD Placement on Mitochondrial Metabolism, $70,000; Holland, William, Juvenile Diabetes Research Fdn., Sphingosine Kinases in Beta Cell Survival and Proliferation, $150,000; Kenkel, Jeffrey, Aesthetic Surgery Educ. & Research Fdn., Trial Evaluating Radiofrequency and Hybrid Fractional Laser for Vaginal Rejuvenation, $60,632; Liu, Yi, CPRIT, DNA Damage-Induced Small Noncoding RNAs: Mechanisms and Their Role in Cancer, $300,000; Oh, Dayoung, American Heart Assoc., Role of FFAR4 in Metabolic Syndrome, $77,000;

Olson, Eric (Fellow B. Kutluk Cenik), American Heart Assoc., Deciphering Role of Twist in Epicardial EMT and Development, $26,844; Pfeiffer, Julie, Burroughs Wellcome Fund, Seminar Award for Dr. Andy Mehle, $1,000; Shakil, Amer, Texas Higher Educ. Coordinating Board, Residency Expansion Award, $150,000; Siegwart, Daniel, American Cancer Soc., Functional Polyester Library for Enhanced and Selective miRNA Delivery, $197,988; Sperandio, Vanessa, Burroughs Wellcome Fund, Seminar Award for Marvin Whiteley, Ph.D., $1,000;

Story, Michael, CPRIT, Recruitment of Established Investigator, $1,200,000; Sun, Xiankai, Texas A&M Univ./CPRIT, Improving Contrast for Antibody-Based Tumor Detection Using PET, $54,256; Sutphin, Patrick, Interventional Radiology Fdn., Lipoprotein Omega-3 Fatty Acid Nanoparticles: Novel Transarterial Treatment for Hepatocellular Carcinoma, $50,000; Winter, Sebastian, American Cancer Soc., Manipulation of Gut Microbiota to Prevent Colitis-Associated Cancer, $198,000; Yan, Nan, Washington Univ. in St. Louis/Clark Fdn., Molecular Mechanism of RVCL Disease, $180,000; Ye, Jin, Welch Fdn., Biochemical Characterization of the Fatty Acid-UAS Domain Interaction, $65,000.

Industry Sponsored Awards, dollar amounts not available

Anderson, Larry, Merck Sharp & Dohme, Phase 3 Study of Lenalidomide and Low-Dose Dexamethasone for Multiple Myeloma; Dowell, Jonathan, Genentech, Phase 2 Study of Atezolizumab Monotherapy for Metastatic Non-Small Cell Lung Cancer; Iannaccone, Susan, Sarepta Therapeutics, Study of SRP-4045 and SRP-4053 for Duchenne Muscular Dystrophy; Inanoglu, Didem, Ipsen Biopharma, Phase 4 Study of Dysport in Pediatric Lower Limb Spasticity; Kerwin, Diana, Avid Radiopharma, 18F-AV-1451 PET Imaging for Frontotemporal Dementia; Khan, Saad, Eli Lilly, Study of Erlotinib for Metastatic Non-Small Cell Lung Cancer; Mayo, Marlyn, Mallinckrodt Pharma, Study of Terlipressin for Hepatorenal Syndrome Type 1;

McDonagh, David, Lungpacer Medical, Percutaneous Temporary Placement of Phrenic Nerve Stimulator for Diaphragm Pacing; Menon, Neethu, Diagnostica Stago, Thrombin Generation in Children with Sickle Cell Anemia; Rahimi, Assal, Accuray, Phase 1 Study of Cyberknife Partial Breast Irradiation; Rohatgi, Anand, Merck Sharp & Dohme, Understanding Change in HDL Function in High-Risk Multi-Ethnic Populations; Toups, Marissa, Allergan Pharma, Phase 2 Study of GLYX-13 for Major Depressive Disorder; Trivedi, Madhukar, Janssen Research & Dev., Study of Intranasal Esketamine plus Oral Antidepressant for Treatment-Resistant Depression; Troendle, David, Exalenz Bioscience, Study of BreathID Hp and BreathID Lab Systems in Pediatric Population.