Welcome to the Hamon Center for Regenerative Science and Medicine
The Hamon Center for Regenerative Science and Medicine has three overarching goals:
- To answer fundamental questions regarding the mechanisms of tissue and organ formation and disease
- To discover strategies for tissue repair and regeneration based on a solid foundation of knowledge
- To educate future generations of scientists and clinicians who will develop this new scientific knowledge and translate it into novel human therapies
News and Announcements
Seminar Series: “C. elegans surveillance of conserved cellular components to detect and defend pathogen attacks, real or imagined"
Gary Ruvkun, Ph.D., Professor, Department of Genetics, Harvard Medical School – Wednesday, September 27, noon-1 p.m., South Campus Auditorium D1.502 (Lunch provided at 11:45 a.m. for attendees.)
Hair shaft progenitors create a niche for hair growth and pigmentation
Researchers at UT Southwestern Medical Center’s Hamon Center for Regenerative Science and Medicine identified hair matrix progenitors that regulate hair growth and pigmentation.
Gene-editing alternative corrects Duchenne muscular dystrophy
Researchers at UT Southwestern Medical Center successfully used the new gene-editing enzyme CRISPR-Cpf1 to correct Duchenne muscular dystrophy in human cells and mice.
Myomixer is fundamental to muscle formation
Researchers at UT Southwestern Medical Center discovered a small protein named Myomixer that is essential for the formation of skeletal muscle.
Retinoblastoma protein controls growth, survival and neuronal migration in human cerebral organoids
Researchers at UT Southwestern Medical Center’s Hamon Center for Regenerative Science and Medicine identified that the depletion of the tumor suppressor retinoblastoma protein disrupted growth, survival and neuronal migration in human cerebral organoids. These results demonstrated that human cerebral organoids are a powerful tool with which to study human brain development in a dish. This work was published in Development Issue 144(6):1025-1034.
A new Twist in adult skeletal muscle growth and regeneration
Researchers at UT Southwestern Medical Center’s Hamon Center for Regenerative Science and Medicine identified an interstitial progenitor cell, characterized by Twist2 expression, that is highly myogenic, forms type IIb/x myofibres and contributes to regeneration in adult skeletal muscle. This work was published in Nature Cell Biology and featured in the News and Views entitled: “Twist of fate for skeletal muscle mesenchymal cells" written by Goloviznina & Kyba.
Cancer drug could double as a weapon against heart disease, UTSW research shows
Researchers at UT Southwestern Medical Center discovered a developmental anticancer agent that promotes the regeneration of damaged heart muscle.
Choreographing the microRNA-target dance
Molecular biologists at UT Southwestern Medical Center uncovered a new mechanism that choreographs the complex molecular interaction between microRNA and messengerRNA.