Cecil H. and Ida Green Center for Reproductive Biology Sciences

Mission

To promote and support cutting-edge, integrative, and collaborative basic research in female reproductive biology, with a focus on signaling, gene regulation, and genome function.

Overview

The Cecil H. and Ida Green Center for Reproductive Biology Sciences is an endowed basic science research center at UT Southwestern Medical Center under the direction of Dr. W. Lee Kraus, Professor and Vice Chair for Basic Sciences in the Department of Obstetrics and Gynecology, and the Cecil H. and Ida Green Distinguished Chair in Reproductive Biology Sciences. The Green Center is affiliated with the Department of Obstetrics and Gynecology, chaired by Dr. Steven Bloom.

Situated primarily in the Harry S. Moss Clinical Science Building (J) on the South Campus, the Green Center is a state-of-the-art research facility housing University research labs as well as molecular biology and computational genomic cores for use by members of the Green Center.

The Green Center faculty consists of eight faculty from the Department of Obstetrics and Gynecology, along with more than 20 additional members from a variety of other departments across campus. Each work in diverse areas of reproduction, development, gene regulation, and genomics. As a result, the Green Center plays a key role in promoting the study of reproduction, development, gene regulation, and genomics at UTSW.

The Science of the Green Center

Ob/Gyn collage: from egg and sperm to newborn child

The research faculty members of the Green Center are addressing fundamental and applied questions related to reproductive biology in a broad sense, as well as related areas relevant to reproductive biology.

Classical reproductive biology:

  • Oocyte maturation
  • Fertilization
  • Development
  • Pregnancy
  • Parturition

Related areas relevant to reproductive biology:

  • Endocrinology
  • Oncology
  • Stem cells
  • Metabolism
  • Inflammation
  • Immunity

The focus of the research in the Green Center is on nuclear regulation, but includes other aspects of cellular regulation as well. Key research areas include:

  • Chromatin structure and gene regulation
  • Epigenetics
  • Nuclear endpoints of cellular signaling pathways
  • Genome organization and evolution
  • RNA Biology

Researchers in the Green Center use the tools of:

  • Biochemistry
  • Molecular biology
  • Structural biology
  • Animal models
  • Genomics
  • Proteomics
  • Bioinformatics
  • Computational biology