Awards for December 2015

Federal Awards

Badawy, Mohamed, Med Coll Wisconsin/NIH, Use of Mechanism of Injury for the Identification of Severely Injured Children, $139,057; Burgess, Shawn, NIH, Factors Controlling Metabolic Flux in Liver by NMR Isotopomer Analysis, $311,242; Casey, Brian, Univ of Alabama/NIH, Chronic Hypertension and Pregnancy-CHAP Clinical Coordinating Center, $132,159; Cleaver, Ondine, NIH, GTPases as Molecular Gatekeepers of Cytoskeletal and Cellular Polarization During Endothelial Tubulogenesis, $378,505; D'Orso, Ivan, NIH, Functional Interplay Between Tat and Novel Host Co-Factors in HIV Transcription, $395,449; Eisch, Amelia, NIH, New Horizons in Adult Neurogenesis, $120,353; Elmquist, Joel (Fellow C. Castorena), NIH, Regulation of Energy Homeostasis via Cannabinoid 1 Receptors in the Ventral Media, $52,406; Gatson, Joshua, Meso Scale Diagnostics/Dept of Defense, Fieldable Multiplex Test for TBI Assessment, $36,398;

Gruchalla, Rebecca, Univ of Wisconsin/NIH, Inner City Asthma Consortium MUPPETS, $69,251; Gruchalla, Rebecca, Univ of Wisconsin/NIH, Registry for Asthma Characterization and Recruitment 2, $67,649; Gruchalla, Rebecca, Univ of Wisconsin/NIH, Inner City Asthma Consortium CoNAC, $34,416; Hsia, Connie, NIH, Nanoparticle Drug Delivery in Post-Pneumonectomy Compensatory Lung Growth, $629,683; Idris, Ahamed, Mount Sinai Sch of Med/NIH, Community VOICES 3: Views on Informed Consent in Emergency Situations, $53,864; Kane, Alex, Mount Sinai Sch of Med/NIH, Craniosynostosis Network, $15,900; Kennard, Beth, Johns Hopkins Univ/NIH, IMPAACT Management Oversight Group, $12,444; Kittler, Ralf, NIH, Development of Small Molecules for ERG Ablation in Prostate Cancer, $369,718; Konopka, Genevieve (Fellow D. Araujo), National Science Fdn, Graduate Research Fellowship Program, $46,000;

Le, Lu, Indiana Univ/NIH, Developmental and Hyperactive Ras Tumor SPORE, $87,120; Leavey, Patrick, Children’s Hosp Phila/NIH, STUDY CHAIR: NIH National Clinical Trials Network (NCTN) Grant, $30,000; Leavey, Patrick, Children’s Hosp Phila/NIH, National Clinical Trials Network (NCTN)-Per Case Reimbursement, $27,500; Luo, Weibo, NIH, The Role of JMJD2C in HIF-1 Activation and Breast Cancer Progression, $224,091; McAdams, Carrie, NIH, Neurobiology of Social Thinking in Anorexia, $171,612; Mitchell, Ron, Children’s Hosp Phila/NIH, Impact of Mild Sleep-Disordered Breathing on Children's Health, $180,545; Morrison, Sean (Fellow M. Murphy), NIH, Neural Regulation of the Hematopoietic Stem Cell Niche, $54,194; Olson, Eric & Bassel-Duby, Rhonda, NIH, Deciphering the Role of a Novel Micropeptide in Cardiac Function and Dysfunction, $554,826; Phillips, Margaret, NIH, Lead Optimization of DHODH Inhibitors for Malaria, $595,447;

Raskin, Philip, Univ of South Florida/NIH, TrialNet Affiliate Services, $264,983; Raskin, Philip, Case Western Reserve Univ/NIH, Epidemiology of Diabetes Intervention & Complication, $33,290; Rosenbaum, Daniel, NIH, Molecular Mechanism of a Master Regulator of Sterol Homeostasis, $277,395; Snell, William, NIH, Gamete Membrane Adhesion and Fusion During Fertilization, $282,916; Sperandio, Vanessa, NIH, Quorum Sensing Regulation of EHEC Virulence Genes, $477,000; Stull, James, UT HSC Houston/NIH, Mutations in Smooth Muscle Contractile Proteins: Pathway, $402,580; Stull, James, NIH, Signal Transduction Mechanisms to Myosin Phosphatase, $391,537; Sun, Xiankai, SRI Intl/NIH, Multi-Layered Valency: A Novel Design of Peptidic Imaging Agents for avß6, $149,624; Toto, Robert, Dartmouth Coll/NIH, Development of a Cross-CTSA IRB Reliance Agreement, $68,299; Tu, Benjamin, NIH, Metabolic Signals Driving Cell Growth and Proliferation, $369,402;

Turer, Christy, NIH, Primary Care, Communication, & Improving Children's Health, $138,310; van Oers, Nicolai, NIH, Long Noncoding RNAs and Their Contribution to 22q11 Deletion Syndrome, $431,520; Wang, Jing, NIH, Next Generation 4D-CBCT for Lung Cancer Radiation Therapy, $327,375; Wang, Yingfei, NIH, The Role of a Novel AIF-Associated Nuclease PAAN1 in Neuronal Injury, $224,100; Whitworth, Louis, Johns Hopkins Univ/NIH, Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III (MISTIE III), $25,534; Wyckoff, Myra, RTI Intl/NIH, NICHD Neonatal Research Network Capitation Funding, $24,718; Yu, Gang, NIH, Gamma-Secretase and Myelin: A Paradigm Shift in Brain Disorders, $313,031.

Nonfederal Awards

Ariizumi, Kiyoshi, CPRIT, Targeting the DC-HIL Receptor for Anti-Cancer Immunotherapy, $381,009; Chen, Zhijian, Lupus Research Inst, Roles of the cGAS Pathway in Lupus, $250,000; Danuser, Gaudenz, CPRIT, Recruitment of Established Investigators, $695,252; Frohman, Elliot, UT Dallas/Natl Multiple Sclerosis Soc, Auditory Processing in MS, $33,000; Goodman, Joel (Fellow Q. Gao), Amer Heart Assoc SW, Molecular Understanding of the Function of Perilipin, $70,000; He, Yu-Guang, Vital Art and Science/Tx Emerging Tech Fund, Low-Cost Home Vision Self-Test, $48,297; Hedayati, Susan, Univ of Washington/PCORI, Treatment Options for Depression in Patients Undergoing Hemodialysis, $174,185; Herz, Joachim, Univ of Calif San Fran/Bluefield PJ To Cure FTD, Progranulin-Enhancing Drug Discovery and GRN Lipidomics, $225,000; Hulleman, John (Fellow K. Vu), Research to Prevent Blindness, RPB Medical Student Eye Research Fellowship, $30,000;

Jain, Raksha, Cystic Fibrosis Fdn, Therapeutics Development Center, $73,586; Kim, Roy, Jaeb Center/Novo Nordisk, Pediatric Diabetes Consortium - Type 2 Diabetes Registry, $3,000; Kraus, William (Fellow R. Gupte), Amer Heart Assoc SW, PARP-1 in Macrophages, $50,432; Levine, Benjamin, Texas Health Presbyterian Hosp, Program in Exercise and Environmental Medicine, $57,783; Mattrey, Robert, CPRIT, Developing and Translating Ultrasound and Nanotechnology to Enhance Cancer Imaging, $1,200,000; Mirzaei, Hamid, CPRIT, Develop Cutting-Edge Proteomics Core Facility Based on High Resolution, High Accuracy Mass Spectrometry and High Throughput, Web-Based Bioinformatics Technology, $830,000; Morrison, Sean (Fellow K. Ahlqvist), Embl Heidelberg, Deciphering the Mitochondrial Fingerprint of Hematopoietic Stem Cell Aging, $57,636; Olson, Eric (Fellow M. Morales France), Pew Latin Amer Fellows Prgm, Transcriptional Control of Fibroblast to Cardiomyocyte Reprogramming, $95,000;

Reynolds, Kimberly, Gordon and Betty Moore Fdn, Decoding the Genome Using Evolutionary Statistics, $300,000; Rogers, Zora, Boston Children’s Hosp, Retrospective Analysis of Aplastic Anemia, $6,000; Rohatgi, Anand, Amer Heart Assoc, Determining the Genomic and Lipidomic Correlates of HDL Cholesterol Efflux and HD, $160,000; Rosen, Michael (Fellow F. Rustam Ali), Amer Heart Assoc SW, NMR Studies of Actin Monomer Dynamics and Their Roles in Actin Filament Dynamics and Heart Disease, $48,680; Rosenbaum, Daniel (Fellow L. Clark), Amer Heart Assoc SW, Structural Mechanism of Cholesterol Homeostasis by Scap, $26,000; Sathe, Meghana, Cystic Fibrosis Fdn, TDC Additional Research Coordinator Award, $90,396; Sathe, Meghana, Cystic Fibrosis Fdn, Therapeutics Development Center, $73,586; Turley, Stephen, Rett Syndrome Research Trust, Impact of 2HPßCD Treatment on Male Mecp2-Deficient Mice, $156,180;

Zhang, Chengcheng, CPRIT, New Antibody Therapy for Treating Leukemia, $683,508; Zhu, Hao, CPRIT, Targeting the SWI/SNF Chromatin-Remodeling Complex in Liver Cirrhosis and Hepatocellular Carcinoma, $528,049. 

Industry Sponsored Awards, dollar amounts not available

Abu-Hijleh, Muhanned, Spiration Valve System in Air Leaks – VAST, Spiration Inc; Antonelli, Jodi, Phase 2B Study of Multiple Doses of ALLN-177 in Recurrent Calcium Oxalate Kidney Stone Formers with Hyperoxaluria, Premier Research Group/Allena Pharm; Aquino, Victor, Remestemcel-L, Ex-vivo Cultured Adult Human Mesenchymal Stromal Cells for Pediatric Pts, Quintiles/Mesoblast Sarl; Arnold, Susan, Lacosamide as Adjunctive Therapy in Sbjs with Epilepsy 1 Month to 4 Yrs of Age with Partial-Onset Seizures, PRA Health Sciences/UCB Biosciences; Beg, Muhammad, Phase 2 Study of Oral ENMD-20, Casi Pharm Inc; Beutler, Bruce, Novel Pathways Mediating Glucose Uptake into Skeletal Muscle, Pfizer Inc; Bird, John, Evaluation of Hypoallergenicity of New Extensively Hydrolyzed Formula, Clinipace Worldwide/Nestec;

Brugarolas, James, Evaluation of Tumor Microarray with Samples of Tumor Grafts with Integrin-specific antibodies, Arrowhead Research Corp; Chen, Zhijian, Small Molecules that Target cGAS Pathway, Immune Sensor LLC; Cheng, Jonathan, Response to Electrical Stimulation of Peripheral Nerves, Nerves Inc; Chin, Kelly, Medical Therapy for Pulmonary Hypertension in Unrepaired Atrial Septal Defect, Ohio State Univ/Gilead Sciences; Falck, Russell, Design and Synthesis of EET Mimetics; Servier Project, Med Coll of Wisconsin; Green, Carla, Sleep Research Project, Univ of Tsukuba; Jain, Raksha, Phase 3 Study of VX-661 with Ivacaftor in Sbjs 12+ yrs with Cystic Fibrosis, Greenphire/Vertex Pharm;

Journeycake, Janna, Phase 3 Study of Coagulation Factor VIIa (Recombinant) in Congenital Hemophilia A or B Pts 6 mos. to 12 yrs. with Inhibitors to Factor VIII or IX, PSI Pharm Support America/LFB USA; Kaza, Vaidehi, Evaluation of DSA Post Lung Transplant, Washington Univ in St. Louis; Lee, William, Phase 2 Study of MK-5172 and MK-3682 with Either MK-8742 or MK-8408 in Sbjs with Chronic HCV GT1 and GT2 Infection, DrugDev/Merck Sharp & Dohme; Lee, William, Phase 2 Study of MK-5172 and MK-3682 with Either MK-8742 or MK-8408 in Sbjs with Chronic HCV GT3 Infection, DrugDev/Merck Sharp & Dohme; Levine, Benjamin, Hemodynamic and Sympathetic Neural Response to Cardiac Contractility Modulation, Impulse Dynamics (USA) Inc; Lotan, Yair, Phase 3 Comparative Study of Blue and White Light Cystoscopy in Detection of Bladder Cancer Patients, Cato Research/Photocure ASA; McCavit, Timothy, Evaluation of Repeat Administration of Purified Poloxamer 188 in Vaso-Occlusive Crisis of Sickle Cell Disease, Mast Therapeutics Inc;

Minei, Joseph, Phase 3 Study of AB103 in Pts with Necrotizing Soft Tissue Infections, AtoxBio; Olson, Daiwai, Management of Acute Stroke Pts on Treatment with New Oral Anticoagulants: ARAMIS Registry, Duke Clin Res Inst/Daiichi Sanko; O'Suilleabhain, Padraig, Multiple Ascending Dose Study of IV Admin BMS-98168 in Pts with Progressive Supranuclear Palsy, Covance/Bristol-Myers Squibb; Phillips, Margaret, Blood Nucleotide Analysis After Dosing of Dihydroorotate Dehydrogenase Inhibitors in Animals and Man, Medicines for Malaria Venture; Raj, Ganesh, Validating the Explant Platform in Human Cancers, C-Diagnostics LLC; Scherer, Philipp, Hepatic Stellate Cell Activation in Non-Alcoholic Fatty Liver Disease, Eli Lilly & Co; Scherer, Philipp, Insulin Sensitizer New Target Collaboration, Merck & Co Inc;

Slone, Tamra, Phase 2 Study of Lenalidomide in Ped Sbjs 1-18 Yrs with Acute Myeloid Leukemia, Children’s Hosp Phila/Celgene; Story, Michael, Novocure TTF and TTF Plus Radiation; Ph1 in Vitro Studies, Novocure; Timaran, Carlos, Zenith p-Branch Pivotal Study, Cook Res Inc; Torres, Fernando, Phase 2b Trial of GS-5806 in Lung Transplant Recipients with Respiratory Syncytial Virus Infection, Gilead Sciences Inc; Trivedi, Madhukar, Study of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adults with Treatment-resistant Depression, Janssen Res & Dev LLC; Vusirikala, Madhuri, Phase 1/2 Study of Donor BPX-501 T Cell Infusion for Minimal Residual Disease Hematologic Malignancies Post-Allogeneic Transplant, Bellicum Pharm.