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Neuro Models Facility Services & Fees

The Neuro-Models Facility (NMF) facilitates scientific research of nervous system function and enhances the development and testing of novel therapeutic strategies for the treatment of nervous system disorders. 

Procedures are available for rodents (mice and rats). New and/or modified procedures can potentially be developed based on client interests. All procedures or services can be performed on a full-service basis by our expert staff, or we can train you how to perform the procedures or testing independently, and thereafter, the core resources can be used on a rental basis.

Please remember to acknowledge your usage of our facility resources in your publications using our established Research Resource Identifier code anywhere in your methods or acknowledgements: RRID: SCR_022529. This is critical for us to maintain support for the core. 

Surgical Approaches

Surgical approaches to model production and assessment.

  • Stroke
    • tMCAo (transient middle cerebral artery occlusion model) -- mouse only
    • PT (photothrombotic model) -- mouse only
    • TTC metabolic staining (acute assessment of stroke lesion volume)
  • Traumatic Brain Injury (TBI)
    • TBI-CCI (controlled cortical impact model)
    • TBI-CH (closed head noninvasive impact model)
  • Stereotaxic injection (ICI or ICV) of neuro-tracer, virus, drug, cell suspension, etc.
  • Osmotic minipump implant (sq or sq+intracranial cannula)
  • CSF collection (terminal)
  • Electrode implantation for e-phys recordings (EEG, EMG) -- mouse only

Fees

  • Surgical Procedures
    ServiceFee (UTSW user)Unit
    tMCAo, 60 min $284 each animal
    tMCAo, sham $109 each animal
    pMCAo (filament placement only) $124 each animal
    PT-laser $156 each animal
    PT-laser, sham (full) $140 each animal
    PT-laser, sham (anes + RB) $18 each animal
    TBI-CCI (skull open) $226 each animal
    TBI-CCI (sham) $202 each animal
    TBI-CCI (sham) $202 each animal
    Stereotaxic injection, x1 (any agent) $180 each animal
    S-tax injection, additional (same animal, new track) $63 each animal
    S-tax injection, additional (same animal, same track) $46 each animal
    Minipump implant, sq $46 each animal
    Minipump implant, sq+brain $202 each animal
    CSF collection, rat, non-survival $94 each animal
    CSF collection, mouse, non-survival $70 each animal
    Telemetry implant - EEG/EMG (DSI) $234 each animal
    Generic (new) surgery procedure variable please inquire

Behavioral Testing of Sensorimotor Functions

  • Rotorod test
  • Grip strength test
  • Ladder walk test (with manual video scoring)
  • Cylinder test
  • Corner test -- mouse only
  • Forelimb reach-and-retrieve task -- rental use only
  • Pole test

Fees

EEG Recording

In vivo electrophysiological recording (EEG, EMG), including chronic or acute, with time-synchronized video.

Fees

  • EEG Recording
    CategoryFee (UTSW user)Unit
    EEG Recording - DSI system - self-use $20 hourly
    EEG Recording - TDT system - self-use $27 hourly
    EEG Recording - DSI system - per day per animal, core-performed $20 flat
    EEG Recording - setup/takedown fee for multi-day, core-performed $79 hourly

Additional service areas

  • Rental Usage (self-use)
    CategoryFee (UTSW user)Unit
    Surgery station usage (access granted after training) $31 hourly
    Behavior station usage (access granted after training) $24 hourly
    Resource Rental $15 per day
  • Miscellaneous
    CategoryFee (UTSW user)Unit
    Hourly core performed service charge, generic $31 hourly
    Procedure training by core staff $24 hourly
    Facility orientation by core staff $15 per day