Texas Cancer Cell Imaging Core
The Cancer Cell Imaging Core (CCIC) streamlines the imaging pipeline with fully automated operations, enabling researchers to visualize cancer processes with unprecedented resolution.
Technology that Empowers Research
CCIC provides high-resolution 3D light-sheet imaging of cancer in tissue contexts, delivering multiscale, multiplexed data and quantitative analysis powered by high-performance computing. We enable in situ visualization of cell states and interactions across multiple scales—from whole tissues to subcellular resolution.
CCIC streamlines:
- Antibody validation
- Tissue clearing
- Expansion microscopy
- Cyclic multiplexed imaging
- Live imaging of spheroids
Fully automated operations are supported by robotics and high-performance computing.
By integrating spatially resolved transcriptional and metabolic data with quantitative imaging, and providing access to powerful, cloud-based analysis tools via a user-friendly web interface, CCIC empowers researchers to uncover the functional impact of oncogenic processes in realistic tissue environments.
Supporting Cutting-Edge Research
Operating on a fee-for-service model with robust training and support, CCIC facilitates cutting-edge cancer research across UT Southwestern and partnering institutions in Texas through scalable, standardized, and reproducible imaging pipelines that are unique in the field.
CCIC imaging services combine:
- State-of-the-art multiscale imaging
- Tissue clearing
- Thick-tissue cyclic immunofluorescence
- Expansion microscopy
- Tailored image analysis
We primarily serve our UTSW research community, however, CCIC will also collaborate with other institutions state-wide.