2024 Article Archive
Essential tremor triples dementia risk, UTSW study shows
Patients with a common movement disorder known as essential tremor (ET) developed dementia at three times the rate of similarly aged people in the general population, a study led by UT Southwestern Medical Center researchers shows.
Drug targeting clear cell renal cell carcinoma shows promising approach
– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).
Simulation reveals new mechanism for membrane fusion
– An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.
Drug combo shows promise in restoring cardiac function
Heart failure patients may one day be able to restore cardiac function with medications that revive the body’s ability to regenerate heart muscle, a novel study at UT Southwestern Medical Center suggests.
Oral contraceptive use may reduce muscle-tendon injuries
Women who take oral contraceptives may be significantly less likely to experience certain musculoskeletal injuries than women who do not take the drugs or men, according to a study by UT Southwestern Medical Center.
How to reduce the stress when caring for someone with dementia
Caring for someone with dementia or Alzheimer’s disease is challenging. In addition to the financial and physical demands, many caregivers are unprepared for the stress of trying to effectively communicate with a loved one who may be prone to agitation, verbal aggression, and hallucinations.
Unraveling the mystery of misfolded proteins in the brain
Proteins known as oligomeric chaperones help suppress the formation of misshaped proteins that cause a variety of degenerative and neurodegenerative diseases, such as Alzheimer’s, Huntington’s, and Parkinson’s.
Inducing labor with drug vaginally shows benefits in study
Labor induction with vaginal misoprostol during childbirth achieves vaginal delivery rates similar to the oral alternative while significantly reducing the need for oxytocin, the most commonly used labor-inducing drug, UT Southwestern Medical Center researchers report.
UT Southwestern scientists discover antiviral immune pathway
By focusing on a poxvirus protein, a team led by UT Southwestern Medical Center scientists has discovered an antiviral immune pathway that broadly fights a wide variety of viruses.
UTSW Research: Food allergies, weight-loss surgery, and more
Millions of children have food allergies, many of which can cause severe illness or death. In a study published in the New England Journal of Medicine, a team of researchers, including those from UT Southwestern, shows in a phase three clinical trial that an antibody-based therapy called omalizumab may inhibit food allergy reactions when delivered repeatedly over time.