Center for Depression Research and Clinical Care

Despite great progress in uncovering the underlying mechanisms of many diseases over the last several decades, modern medicine has just begun to understand the human brain—the body’s most complex system and medicine’s greatest mystery.

Our Vision

A future free from the burden of depression.

Our Mission

  • Improving the lives of people those suffering from depression and bipolar disorder
  • Revolutionize our understanding of the biological underpinnings of depression
  • Accelerate scientific discovery
  • Disseminate advancements

Our Research

For more than two decades, Dr. Madhukar Trivedi and his colleagues at UT Southwestern have conducted cutting-edge research to improve the treatment of depression, including the largest study-to-date examining appropriate treatment sequences for depression.