Center for Depression Research and Clinical Care

Despite great progress in uncovering the underlying mechanisms of many diseases over the last several decades, modern medicine has just begun to understand the human brain—the body’s most complex system and medicine’s greatest mystery.

Our Vision

A future free from the burden of depression.

Our Mission

  • Transform the diagnosis and treatment of depression and bipolar disorder
  • Revolutionize our understanding of the biological causes of depression and bipolar disorder
  • Accelerate scientific discovery
  • Disseminate new findings to real practice

Our Research

For more than two decades, Dr. Madhukar Trivedi and his colleagues at UT Southwestern Medical Center have conducted cutting-edge research to improve the treatment of depression, including the largest study-to-date examining appropriate treatment sequences for depression.