Patient Care
The Cain Bladder Center is pleased to recognize that as our patient load increases, the volume demands are being met, and there is still capacity to expand! Our patient navigator, Yvette Soriano, has played a positive role in arranging timely appointments and closely following up on patients for subsequent tests and procedures. We've been tracking the increase in patient care provided, and also sources of referral. Additionally, we offer a quarterly newsletter tailored to patients and their families to describe ongoing activities and efforts at the Cain Bladder Center.
As a Cain Bladder Center patient or site visitor, we are pleased to present several clinical studies about recurrent urinary tract infections in women that are currently being conducted at the Cain Bladder Center. If you have any questions, please UTSWUTI@UTSouthwestern.edu or call us at 214-645-8787.
Daily Antibiotic vs. Daily Antibiotic and Surgical Intervention for recurrent UTI (rUTI)
STU: 2024-1187: A multi-centric randomized trial of daily nitrofurantoin versus bladder fulguration plus daily nitrofurantoin for the long-term management of cystitis in women with recurrent urinary tract infections
Purpose:
To compare the efficacy of daily antibiotic treatment to daily antibiotic treatment and surgical intervention.
Inclusion:
Women, ages 18-85, with a history of recurrent urinary tract infections. Excluded are pregnancy, using self-start antibiotics, uncontrolled diabetes, or kidney/liver disease.
Includes:
This study includes 8 visits over 30 months and compensation of up to $800. All costs related to study including office visits, antibiotics, lab testing, and surgical intervention will be covered.
Email the Bladder Health team or call 214-645-8787
D-mannose for recurrent UTI (rUTI) prophylaxis on post-menopausal women
STU: 2024-1090: A randomized controlled trial of D-mannose for the prophylaxis of recurrent urinary tract infections in post-menopausal women
Purpose:
To elucidate the efficacy of D-mannose on preventing uncomplicated rUTI.
Inclusion:
We are recruiting post-menopausal women between 55-85 years old, who have been diagnosed with recurrent UTI, and are interested in considering a preventive approach.
Includes:
This study requires 7 visits over a 12-month period. Each visit will be compensated, for a total of up to $500. The D-mannose or placebo capsules will be provided by the research team. At each visit, we will obtain a urine sample and two vaginal/perianal swabs.
Email the Bladder Health team or call 214-645-8787
Menopausal women with active UTIs or women who never had a UTI
STU-2019-0968: Evolution of the genitourinary microbiome in women with recurrent urinary tract infections
Purpose:
We are interested in seeing the changes in the urinary bacterial environment over time. By comparing women with or without UTI, we hope to identify beneficial bacteria that can be used as alternate therapies for UTIs.
Inclusion:
We are recruiting women over the age of 55 (post-menopausal) with active UTIs or women who have never had any UTIs (or did not have a UTI in the past 10 years).
Includes:
This study requires 4 visits over a 3- month period. Compensation is available for all 4 visits, up to $375 in total. At each visit, we will obtain a urine sample and two swabs around the genital area.
Email the Bladder Health team or call 214-645-8787
Urinary Tract Infection & Antibiotic Treatment
STU-2023-0653: A single center, randomized, non-inferiority trial of empiric versus culture-based antibiotic therapy for UTIs in adult women with a history of recurrent UTIs
Purpose:
To compare the efficacy of antibiotic treatment prescribed empirically or based on urine culture for an acute cystitis episode in adult women with a history of recurrent urinary tract infections.
Inclusion:
We are recruiting women between 18-85 years old with a documented history of recurrent urinary tract infections, who are experiencing an acute cystitis episode for which they will require an antibiotic treatment.
Includes:
This study requires up to 3 interactions with our research team, first at baseline, second before antibiotic therapy and third one week later. These interactions can be completed over the phone or during an office visit.
Email the Bladder Health team or call 214-645-8787
With the Cain Bladder Center only having been open for just under two years, the Center is already making a lifelong impact in some patients lives.
"Thank you for all you have done for me. Before I was under your care I truly was in despair. I experienced extremely painful UTIs that were debilitating. After many years of suffering, I was grateful to meet you. From my first visit, you treated me with kindness, respect, and compassion. Relying on daily antibiotics was causing me great anxiety. I no longer need to do this. I am so thankful for you and your dedication to helping people like me."
–Cain Bladder Center patient
Results from trials help our medical professionals decide what is best depending on patient needs.