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Drug targeting clear cell renal cell carcinoma shows promising approach: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/april-drug-targeting.html?fbclid=IwZXh0bgNhZW0CMTAAAR0qoz8aKfkpZ4rNlkoFjJ8sV79sQ2-f4lQZnwo4mrwmIuesBO1MZBeXY5k_aem_AW94ESPIrgDPqPPcOV5mP2WhgDKWR5Va4l6-c5sfofp7Ef5re9IgqYH2ny9w9W9k7N0tLdmNlrnLlDUk8umOFYRT

– In a groundbreaking phase one clinical trial led by UT Southwestern Medical Center, a short interfering RNA (siRNA) drug directed to tumor cells, ARO-HIF2, effectively disrupted HIF2α, a key driver of clear cell renal cell carcinoma (ccRCC).

UT Southwestern No. 1 hospital in Dallas-Fort Worth, Best Hospital rankings show: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2022/july-us-news-best-hospital.html?utm_source=facebook&utm_medium=organic&utm_campaign=newsroom&utm_content=usnwrrankings&utm_utm-audience=na&fbclid=IwAR3tY4r24j2gT-WKC5ar4jpT51bBLwVrirgZfpXOMV_c4aSikMhT6vdPJaI

UT Southwestern Medical Center is the No. 1 hospital in Dallas-Fort Worth – the nation’s fourth-largest metro area – for the sixth consecutive year and ranks among the top hospitals nationally in nine specialties ranging from brain to heart to cancer care.

Three drugs target resistant breast cancers driven by HER2 mutations

https://www.utsouthwestern.edu/newsroom/articles/year-2023/nov-triple-therapy-her2.html

A targeted therapy using three different drugs significantly delayed progression and extended survival for breast cancer patients whose HER2 gene is mutated.

News Releases: Newsroom - UT Southwestern, Dallas, TX

https://www.utsouthwestern.edu/newsroom/articles/?search=&phrase=Women's+Health&

Read past stories about the extraordinary work being done and the passionate people behind it.

News Releases: Newsroom - UT Southwestern, Dallas, TX

https://www.utsouthwestern.edu/newsroom/articles/?search=&phrase=pediatrics&

Read past stories about the extraordinary work being done and the passionate people behind it.

Two-step screening strategy could reduce diabetic heart failure: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/dec-could-reduce-diabetic-heart-failure.html

A two-step screening protocol that combines clinical risk assessment with biomarker testing can more effectively identify which patients with Type 2 diabetes need medication to prevent heart failure, according to a study led by UT Southwestern Medical Center researchers.

Cancer cell–immune cell interactions predict immunotherapy response: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/april-cancer-cell-immune-cell-interactions.html

By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with breast cancer will respond to immunotherapies.

Moncrief Cancer Institute debuts new Mobile Screening Clinic funded by Tarrant County : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/march-moncrief-cancer-institute-mobile-screening.html

Moncrief Cancer Institute debuted its new Mobile Screening Clinic prior to the Tarrant County Commissioners Court meeting today. The $1 million, 36-foot cancer screening clinic was funded by Tarrant County through a three-year, $9 million grant awarded to Moncrief Cancer Institute in 2022.

Warfarin use should not disqualify stroke patients from lifesaving clot-removing surgery: Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2023/june-lifesaving-clot-removing-surgery.html

Most stroke patients taking the anticoagulant warfarin were no more likely than those not on the medication to experience a brain bleed when undergoing a procedure to remove a blood clot, UT Southwestern Medical Center researchers report in a new study.

Machine learning sheds light on gene transcription : Newsroom - UT Southwestern, Dallas, Texas

https://www.utsouthwestern.edu/newsroom/articles/year-2024/may-machine-learning-gene-transcription.html

A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters – regions of DNA that initiate the process by which genes produce proteins.