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Obesity A Review for Teachers Outline • The prevalence of obesity & associated medical problems has increased greatly in the US, both among adults & children. • The causes are complex. • Controlling obesity by exercise & diet is difficult. • Drug therapy is not very effective. Surgery may be necessary for severe obesity. How Do We Define Overweight & Obesity? • In adults, obesity is defined by the BMI (Body Mass Index), which is the weight in kilograms divided by height in

Molecular Mechanisms of Circadian Clocks Circadian Rhythms • Endogenous rhythm which persists under constant conditions • Period of approximately 24 hours • Entrainable (reset) by environmental cues such as light and temperature • Temperature compensated - period stays about the same at different temperatures Circadian rhythm of locomoter activity Body temperature cycle Circadian rhythm of melatonin secretion Circadian rhythms of photosynthetic genes in plants

Overview of Gastrointestinal Function George N. DeMartino, Ph.D. Department of Physiology University of Texas Southwestern Medical Center Dallas, TX 75390 The gastrointestinal system Functions of the gastrointestinal system • Digestion • Absorption • Secretion • Motility • Immune surveillance and tolerance GI-OP-13 Histology of the GI tract Blood or Serosal Side Lumenal or Mucosal Side Structure of a villus Villus Lamina propria X X X X X Lumen

Spend a morning at UT Southwestern learning from experts on the foremost topics in women's health.

Microarrays Ralph V. Shohet, M.D. Department of Internal Medicine, UTSWMC Outline 1. Types of microarrays 2. How to make one 3. How to use one Historical perspective 1. Watson-Crick basepairing 2. Southern & Northern analysis 3. Genome project Types of microarrays 1. Synthesized in situ 2. Spotted Types of microarrays 1. Synthesized in situ Short oliogonucleotides (25mers) masked and DOC particularly useful for interrogating small regions of a gene for sequence

STEM CELL CLUB October 18, 2001 12:00 Noon Y6.228 Conference Room STEM CELLS, NK CELLS, and FRIEND VIRUS LEUKEMIA Michael Bennett, Department of Pathology Stem Cells: Gustavo Cudkowicz, Don Metcalf, Roger Foster, and Vinay Kumar Friend Virus: Gustavo Cudkowicz, Richard Steeves, Bob Eckner, Ed Mirand, and Vinay Kumar NK Cells: Vinay Kumar, Dorothy Yuan, Wayne Lai, PA Mathew, and John Schatzle, (faculty) Differentiation: Edwardo Luevano, John Hackett, Michelle Tutt, Tom Moore, Igor