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DR. WOODRING E. WRIGHT BIOLOGY OF AGING Learning objectives: At the completion of the lecture, you should be able to: 1. 2. 3. 4. 5. 6. 7. 8. 9. Define antagonistic pleiotropy Give the rationale for why the “disposable soma” theory of aging can be treated as an example of antagonistic pleiotropy Name four premature aging syndromes, two of which are known to affect DNA repair enzymes Describe why patients with diabetes are thought to show accelerated aging of

STARS Mini-Symposium Skeletal Muscle: Development, Adaptation & Disease “Gain Without Pain” Rhonda Bassel-Duby, Ph.D. Associate Professor of Molecular Biology Diagram of Skeletal Muscle Myoglobin Immunohistochemistry Subtypes of Skeletal Myofibers Type I (slow)Type I (slow) Type Type IIaIIa Type Type IIb IIb (fast)(fast) white, glycolytic fatigue rapidly rapid force development insulin-resistant red, oxidative fatigue-resistant slow contraction insulin-sensitive endurance

Anesthesiology, Yesterday, Today and Tomorrow Adolph H. Giesecke MD. Retired Jenkins Professor and Former Chairman, Anesthesiology and Pain Management, UTX Southwestern Medical Center, Dallas TX. The First Anesthesiologist. 1 ♦"And the Lord God caused a deep sleep to fall upon Adam, and he slept." Genesis 2:21 . Managing Pain Before Anesthesia ♦Local application of cold water, ice or pressure. ♦Plants and extracts. ♦Coca leaves chewed and saliva dripped into

Obesity A Review for Teachers Outline • The prevalence of obesity & associated medical problems has increased greatly in the US, both among adults & children. • The causes are complex. • Controlling obesity by exercise & diet is difficult. • Drug therapy is not very effective. Surgery may be necessary for severe obesity. How Do We Define Overweight & Obesity? • In adults, obesity is defined by the BMI (Body Mass Index), which is the weight in kilograms divided by height in

10/10/2013 1 "From Molecules to Man: The Importance of Molecular Imaging in Clinical Medicine” A. Dean Sherry, Ph.D. Director, Advanced Imaging Research Center, UT Southwestern Medical Center Professor of Radiology, UT Southwestern Professor of Chemistry, UT Dallas ADVANCED IMAGING RESEARCH CENTER A IR C Frontiers in Biomedical Imaging symposium for STARS, Oct. 12, 2013 What is Molecular Imaging? bioluminescence "Anatomy Lesson of Dr. Nicolaes Tulp" by Rembrandt (slightly

Microarrays Ralph V. Shohet, M.D. Department of Internal Medicine, UTSWMC Outline 1. Types of microarrays 2. How to make one 3. How to use one Historical perspective 1. Watson-Crick basepairing 2. Southern & Northern analysis 3. Genome project Types of microarrays 1. Synthesized in situ 2. Spotted Types of microarrays 1. Synthesized in situ Short oliogonucleotides (25mers) masked and DOC particularly useful for interrogating small regions of a gene for sequence

Hepatitis 2003 STARS Program Geri Brown, M.D. Associate Professor Department of Internal Medicine October 4, 2003 Outline n Hepatitis A • Epidemiology and screening • Transmission n Hepatitis B • Epidemiology and screening recommendations • Transmission n Hepatitis C • Epidemiology and screening • Transmission The LiverThe Liver Your liver is a large and important organ in your body Your liver is located behind the lower right part of your ribs What is my liver? Where is my

STEM CELL CLUB October 18, 2001 12:00 Noon Y6.228 Conference Room STEM CELLS, NK CELLS, and FRIEND VIRUS LEUKEMIA Michael Bennett, Department of Pathology Stem Cells: Gustavo Cudkowicz, Don Metcalf, Roger Foster, and Vinay Kumar Friend Virus: Gustavo Cudkowicz, Richard Steeves, Bob Eckner, Ed Mirand, and Vinay Kumar NK Cells: Vinay Kumar, Dorothy Yuan, Wayne Lai, PA Mathew, and John Schatzle, (faculty) Differentiation: Edwardo Luevano, John Hackett, Michelle Tutt, Tom Moore, Igor