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2292 J . Med. Chem. 1996,38, 2292-2301 Increasing Binding Constants of Ligands to Carbonic Anhydrase by Using “Greasy Tails” Jinming Gao, Shuang Qiao, and George M. Whitesides* Department of Chemistry, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138 Received February 13, 1995@ Two series ofpara-substituted benzenesulfonamides have been examined as inhibitors for bovine carbonic anhydrase I1 (CAII, EC 4.2.1.1). Both series have hydrophobic alkyl group R connected

Takahashi Lab's Other Circadian Interests 

Publications for Boyuan Wang, Ph.D.

Learn about Molecular Regulation of Core Circadian Genes

Riboswitches – short segments of mRNA that bind to small molecules and cause a change in expression of proteins coded by the RNA – allows protein expression to self-regulate.

Meet the PI, Joseph Takahashi, Ph.D.

Publications for Samir Parikh, M.D.

About the Takahashi Lab.

Meet the Shahmoradian Lab team.

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