Search

Primarily located in the Advanced Imaging Research Center the Corbin Lab routinely utilizes state-of-the–art small animal imaging systems (MRI, micro-MRI, Optical, micro-CT/SPECT/PET) to characterize rodent models of disease.

Interested in our research? Get in touch to learn more or find out ways to collaborate at Yamamoto Lab.

ARTICLES PUBLISHED ONLINE: 8 DECEMBER 2013 | DOI: 10.1038/NMAT3819 A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals Yiguang Wang1, Kejin Zhou1, Gang Huang1, Christopher Hensley2, Xiaonan Huang1, Xinpeng Ma1, Tian Zhao1, Baran D. Sumer3, Ralph J. DeBerardinis2 and Jinming Gao1* Stimuli-responsive nanomaterials are increasingly important in a variety of applications such as biosensing, molecular imaging, drug

Skip to main content Opportunities We're looking for: Graduate student or Postdoctoral scholar to study TAO protein kinase structures and their nuclear interactions with phosphatases. TAOs can influence the Hippo pathway, influence neuronal development, and survival of certain parasites and viral infections and yet qualify as understudied protein kinases. Postdoctoral scholar to coordinate studies on WNK protein kinases and biological evaluation of inhibitors. Please send a cover letter and CV

Journal of Controlled Release 83 (2002) 427–435 www.elsevier.com/ locate/ jconrel C ombined modeling and experimental approach for the development of dual-release polymer millirods *Feng Qian, Gerald M. Saidel, Damon M. Sutton, Agata Exner, Jinming Gao Cancer-Targeted Drug Delivery Laboratory, Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106,USA Received 3 July 2002; accepted 7 August 2002 Abstract This paper describes a

Skip to main content Research The members of the Cobb lab study the signal-transduction mechanisms of protein kinases, and how kinase structures lead to cell biological functions. We are particularly focused on the contributions of ERK MAP kinases to pancreatic beta cell function and to lung cancers, and on the actions of WNK protein kinases. ERK1/2 Mitogen-activated protein kinases (MAPKs) are universal elements of signaling pathways. ERK2 has long served as a prototype to define properties of

Journal of Controlled Release 91 (2003) 157–166 www.elsevier.com/ locate/ jconrel Q uantification of in vivo doxorubicin transport from PLGA millirods in thermoablated rat livers a ,1 b a a a ,*Feng Qian , Nicholas Stowe , Erin H. Liu , Gerald M. Saidel , Jinming Gao aDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106,USA bDepartment of Surgery, Case Western Reserve University School of Medicine, Cleveland, OH 44106,USA Received 31 October 2002

Trivedi Lab's Mood Disorders Network

Enhancement of Solubility and Bioavailability of �-Lapachone Using Cyclodextrin Inclusion Complexes Norased Nasongkla,1,2 Andy F. Wiedmann,2 Andrew Bruening,3 Meghan Beman,3 Dale Ray,4 William G. Bornmann,5 David A. Boothman,3 and Jinming Gao2,6 Received June 11, 2003; Accepted June 19, 2003 Purpose. To explore the use of cyclodextrins (CD) to form inclusion complexes with �-lapachone (�-lap) to overcome solubility and bio- availability problems previously noted with this drug. Methods

See the Mani Lab's research