Search

The application of Focused Ultrasound (FUS) coupled with IV administration of microbubbles is a unique method whereby localized opening of the BBB can be achieved in a non-invasive manner.

The Center for Depression Research and Clinical Care (CDRC) is nationally recognized for its cutting-edge research in unipolar and bipolar depression. The research conducted within the center brings better understanding of the causes of depression, identifies effective new treatments, and improves

Metabolic reprogramming is now firmly established as a hallmark of cancer

Skip to main content TX-YDSRN Early Intervention & Prevention, Best Care, and Research Screening & Better Care Depression and suicide impact a significant number of Texas youth. TX-YDSRN supports research to better understand depression and suicide and to improve detection and treatment through measurement-based care. Our Programs The Texas Youth Depression and Suicide Research Network (TX-YDSRN) is a research initiative of the Texas Child Mental Health Care Consortium (TCMHCC) , which was

Herz Lab alumni

Local carboplatin delivery and tissue distribution in livers after radiofrequency ablation A. Szymanski-Exner,1 A. Gallacher,2 N. T. Stowe,3 B. Weinberg,1 J. R. Haaga,4 J. Gao1,4 1Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio 2Department of Analytical Chemistry, Ricerca, LLC, Concord, Ohio 3Department of Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio 4Department of Radiology, University Hospitals of

Chung Lab publications

The McDermott Center Human Genetics Clinical Lab is dedicated to help accelerate the pace of human genetic research by providing skilled assistance with collecting and storing biologic specimens.

Enhancement of Solubility and Bioavailability of �-Lapachone Using Cyclodextrin Inclusion Complexes Norased Nasongkla,1,2 Andy F. Wiedmann,2 Andrew Bruening,3 Meghan Beman,3 Dale Ray,4 William G. Bornmann,5 David A. Boothman,3 and Jinming Gao2,6 Received June 11, 2003; Accepted June 19, 2003 Purpose. To explore the use of cyclodextrins (CD) to form inclusion complexes with �-lapachone (�-lap) to overcome solubility and bio- availability problems previously noted with this drug. Methods

The research focus in the Corbin lab investigates strategies that exploits the deviant metabolism of cancer cells (namely the reprogramming of lipid metabolism and altered redox biology) for therapeutic purposes.