Search

Cooperativity Principles in Self-Assembled Nanomedicine Yang Li,† Yiguang Wang,†,‡ Gang Huang,† and Jinming Gao*,† †Department of Pharmacology, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, United States ‡Beijing Key Laboratory of Molecular Pharmaceutics and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100191, China ABSTRACT: Nanomedicine is a discipline that applies nanoscience and

YU ET AL . VOL. 5 ’ NO. 11 ’ 9246–9255 ’ 2011 www.acsnano.org 9246 October 19, 2011 C 2011 American Chemical Society Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery Haijun Yu,† Yonglong Zou,†,‡ Yiguang Wang,† Xiaonan Huang,† Gang Huang,† Baran D. Sumer,§ David A. Boothman,†,‡ and Jinming Gao†,* †Department of Pharmacology, ‡Department of Radiation Oncology, and §Department of Otolaryngology, Simmons Comprehensive Cancer

NATURE BIOMEDICAL ENGINEERING 1, 0006 (2016) | DOI: 10.1038/s41551-016-0006 | www.nature.com/natbiomedeng 1 ARTICLES PUBLISHED: 19 DECEMBER 2016 | VOLUME: 1 | ARTICLE NUMBER: 0006 A transistor-like pH nanoprobe for tumour detection and image-guided surgery Tian Zhao1​†, Gang Huang1, Yang Li1, Shunchun Yang1, Saleh Ramezani2, Zhiqiang Lin1, Yiguang Wang1, Xinpeng Ma1, Zhiqun Zeng1, Min Luo1, Esther de Boer3, Xian-Jin Xie4, Joel Thibodeaux5, Rolf A. Brekken6, Xiankai Sun2, Baran D. Sumer7

Multicolored pH-Tunable and Activatable Fluorescence Nanoplatform Responsive to Physiologic pH Stimuli Kejin Zhou,† Haoming Liu,‡ Shanrong Zhang,†,§ Xiaonan Huang,† Yiguang Wang,† Gang Huang,† Baran D. Sumer,∥ and Jinming Gao*,†,⊥ †Department of Pharmacology, Simmons Comprehensive Cancer Center, ‡Department of Biochemistry, §Advanced Imaging Research Center, and ∥Department of Otolaryngology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States ⊥Department of

Articles https://doi.org/10.1038/s41551-019-0416-1 1Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. 2Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. 3Children’s Research Institute, Departments of Pediatrics, Neuroscience, and Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, TX, USA. 4Department of Otolaryngology, University of Texas Southwestern

    2012;72:3038-3047. Published OnlineFirst April 24, 2012.Cancer Res   Xiumei Huang, Ying Dong, Erik A. Bey, et al.   Kills by PARP1-Induced Programmed Necrosis An NQO1 Substrate with Potent Antitumor Activity That Selectively         Updated Version 10.1158/0008-5472.CAN-11-3135doi: Access the most recent version of this article at: Material Supplementary http://cancerres.aacrjournals.org/content/suppl/2012/04/24/0008-5472.CAN-11-3135.DC1.html Access the most recent supplemental

ARTICLE Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery F. J. Voskuil 1,13, P. J. Steinkamp 2,13, T. Zhao3, B. van der Vegt 4, M. Koller2, J. J. Doff4, Y. Jayalakshmi3, J. P. Hartung5, J. Gao 6,7, B. D. Sumer 6✉, M. J. H. Witjes1, G. M. van Dam 2,8✉ & the SHINE study group* Cancer cell metabolism leads to a uniquely acidic microenvironment in solid tumors, but exploiting the labile extracellular pH differences

Skip to main content Photo Gallery Top Photos Celebrating the new Dr. Bryan Ryder after a successful thesis defense! May 23, 2022 That's DOCTOR Dailu Chen to you! After her thesis defense, July 1, 2022. Everyday Shenanigans Kenny's second-to-last day in Texas Rodeo Goat, June 2018 Kinga’s leaving the Dallas heat behind her... ...but her new Polish substitute came today. Original Market Diner, June 2018 Gregory Blazek Greg’s awesome poster for the SURF summer program, with Dailu Chen greatly

Theranostics 2020, Vol. 10, Issue 7 http://www.thno.org 3340 Theranostics 2020; 10(7): 3340-3350. doi: 10.7150/thno.41239 Research Paper Detection of Lymph Node Metastases by Ultra-pH-Sensitive Polymeric Nanoparticles Zachary T. Bennett1, Qiang Feng1, Justin A. Bishop2, Gang Huang1, Baran D. Sumer3, and Jinming Gao1,3 1. Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas, USA. 2

1310 IEEE TRANSACTIONS ON MEDICAL IMAGING, VOL. 21, NO. 10, OCTOBER 2002 X-Ray Computed Tomography Methods forIn Vivo Evaluation of Local Drug Release Systems Kyle A. Salem, Student Member, IEEE, Agata Szymanski-Exner, Roee S. Lazebnik, Michael S. Breen, Jinming Gao, and David L. Wilson�, Member, IEEE Abstract—Recent advances in drug delivery techniques have necessitated the development of tools forin vivomonitoring of drug distributions. Gamma emission imaging and magnetic resonance imaging