In prior work, my laboratory focused on identifying novel mechanisms of therapy-resistance and progression in breast, prostate and ovarian cancer. 

News for the Conzen Lab.

Contents lists available at ScienceDirect Journal of Controlled Release journal homepage: www.elsevier.com/locate/jconrel Synergistic STING activation by PC7A nanovaccine and ionizing radiation improves cancer immunotherapy Min Luoa,b,1, Zhida Liua,c,1, Xinyi Zhanga, Chuanhui Hanc, Layla Z. Samandia, Chunbo Dongc, Baran D. Sumerd, Jayanthi Leae, Yang-Xin Fuc,⁎, Jinming Gaoa,⁎ a Department of Pharmacology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center

2013;12:2110-2120. Published OnlineFirst July 24, 2013.Mol Cancer Ther    Erik A. Bey, Kathryn E. Reinicke, Melissa C. Srougi, et al.   Directed Programmed Necrosis in NQO1-Positive Breast Cancers −Induced PARP1 Hyperactivation−-LapachoneβCatalase Abrogates   Updated version   10.1158/1535-7163.MCT-12-0962doi: Access the most recent version of this article at:   Material Supplementary   http://mct.aacrjournals.org/content/suppl/2013/07/24/1535-7163.MCT-12-0962.DC1.html Access

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Selected publications of Herz Lab

Critical ReviewsTM in Eukaryotic Gene Expression, 24(1):15-28 (2014) 151045-4403/14/$35.00 © 2014 Begell House, Inc. www.begellhouse.com Review of Poly (ADP-ribose) Polymerase (PARP) Mechanisms of Action and Rationale for Targeting in Cancer and Other Diseases Julio C. Morales,1 Longshan Li,1 Farjana J. Fattah,1 Ying Dong,1 Erik A. Bey,2 Malina Patel,1 Jinming Gao,1 & David A. Boothman1* 1Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75399; 2Department

Micellization DOI: 10.1002/anie.201402525 Chaotropic-Anion-Induced Supramolecular Self-Assembly of Ionic Polymeric Micelles** Yang Li, Yiguang Wang, Gang Huang, Xinpeng Ma, Kejin Zhou, and Jinming Gao* Dedicated to Professor George M. Whitesides on the occasion of his 75th birthday Abstract: Traditional micelle self-assembly is driven by the association of hydrophobic segments of amphiphilic molecules forming distinctive core–shell nanostructures in water. Here we report a surprising

A STING-activating nanovaccine for cancer immunotherapy Min Luo1†, Hua Wang2†, Zhaohui Wang1†, Haocheng Cai2, Zhigang Lu3, Yang Li1, Mingjian Du2, Gang Huang1, Chensu Wang1, Xiang Chen2, Matthew R. Porembka4, Jayanthi Lea5, Arthur E. Frankel6, Yang-Xin Fu7, Zhijian J. Chen2,8* and Jinming Gao1* The generation of tumour-specific T cells is critically important for cancer immunotherapy1,2. A major challenge in achieving a robust T-cell response is the spatiotemporal orchestration of antigen cross

Volunteers Needed For Clinical Research at UT Southwestern. We are conducting studies in obesity, heart disease risk, and type 2 diabetes risk in adults. Please contact us at (214) 648-9014. Compensation available for some studies. For more information please call - 214-648-9014