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Minimal Residual Disease and Metastasis Postdoctoral positions are available in the laboratory of Dr. Srinivas Malladi, Ph.D. - Faculty Profile - UT Southwestern, Department of Pathology at UT Southwestern Medical Center to study the biology of minimal residual disease and metastasis in breast, lung and renal Adenocarcinomas. Malladi Lab - UT Southwestern, Dallas, Texas is focused on understanding how disseminated cancer cells survive, evade immune surveillance and give rise to overt

The Center for Regenerative Science and Medicine aims to promote interactions between scientists and clinicians and build an integrated scientific environment.

Accurate 3D Prints for RVOT Interventions: A Quantitative Study Animesh Tandon, MD, MS1-4; Rami Hallac, PhD4; Nicholas Byrne, MSc5, 6; Maria de las Nieves Velasco Forte, MD5; Gerald F. Greil, MD, PhD1-5; Tarique Hussain, MD, PhD1-5 1Departments of Pediatrics, 2Radiology, and 3Biomedical Engineering, University of Texas Southwestern Medical Center, Dallas, Texas 4Children’s Medical Center Dallas, Dallas, Texas 5Division of Imaging Sciences and Biomedical Engineering, King’s College London

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Harold C. Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource Data Science Collaboration Agreement SCCC-DSSR This agreement is between the DSSR user named below and the Director of SCCC-DSSR, Professor Jeon Lee. By signing this document, user acknowledges and agrees to the conditions listed below. DSSR collaborator (Full Name

User manual for TYGRESS Tomography-Guided 3D Reconstruction of Subcellular Structures (TYGRESS) is a hybrid method, which combines the advantageous features of both single particle cryo-EM and cryo-ET/subtomogram averaging to provide high-resolution structures of macromolecular complexes within their native, cellular environment. In this method, one typical single particle cryo-EM micrograph is acquired (i.e., with an electron dose that is higher than for individual tilt series

Harold C. Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource Data Science On-Demand User Agreement SCCC-DSSR This agreement is between the DSSR client named below and the Director of SCCC-DSSR, Professor Jeon Lee. By signing this document, user acknowledges and agrees to the conditions listed below. DSSR client (Full Name

Protecting Groups in Organic Synthesis-1 Ready Protecting groups are a sad fact of synthetic chemistry They are usually needed, but rarely desired Many syntheses have stalled because of trouble putting on or removing protecting groups 4 basic questions to address when choosing a P.G.: 1. Can I put it on where and only where I want? 2. Can I take it and only it off? 3. Will it survive all future reaction conditions? 4. Will it

1 P(tBu)2 P(tBu)2 CuBr P Pd P P P PBu3 Pt H Et3P Cl PEt3 Ir S R3P H PR3 H S -S PF6 - Ir S R3P H PR3 H P P Pd PF6 - Pt H Et3P Cl PEt3 Py P P Ir S R3P H PR3 H PF6 - Pt H Et3P Py PEt3 Cl Fe Pt H Et3P Py PEt3 P P Cl- Organometallic Reaction Mechanisms Ligand association/dissociation + toluene insoluble (PBu3)nCuBr soluble + active catalyst for cross coupling = NOTE: No ox. state change Ligand Exchange: Associative - common for 16e- complexes

1 R Co(CO)3(OC)3Co O O Δ (OC)3Co O R H O R H2 R H O (OC)4Co R (OC)4Co Co(CO)4 H H (CO)4CoH H2 CO R O H R CO (OC)3Co R (OC)3Co H R H2 R (OC)3Co R The Oxo process -developed in 1938 by Otto Roelen -Principle method for hydroformylation of terminal alkenes industrially -more that 4 million tons aldehyde annually -linear aldehydes more desirable Co2(CO)8 H2/CO (200-300 atm) 120-170 oC linear (normal) branched (iso) + chemical feed stocks linear alcohols