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Journal of Controlled Release 83 (2002) 415–425 www.elsevier.com/ locate/ jconrel N oninvasive monitoring of local drug release in a rabbit radiofrequency (RF) ablation model using X-ray computed tomography a b a aAgata Szymanski-Exner , Nicholas T. Stowe , Roee S. Lazebnik , Kyle Salem , a c a,c ,*David L. Wilson , John R. Haaga , Jinming Gao aDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106,USA bDepartment of Surgery, Case Western Reserve

Skip to main content Evaluation of Indeterminate Liver Lesions (LR-3 and LR-4) The Liver Imaging Reporting and Data System (LI-RADS) standardizes imaging interpretation for liver lesions. Our group has a particular interest in indeterminate liver lesions (LI-RADS-3 and LR-4), which present challenges in clinical decision-making. We have led studies characterizing their natural history, including risk of developing HCC, and defined recommended management algorithms. As a site in the Translational

Meet our Principal Investigator, E. Sherwood Brown, MD, PhD, MBA

Research in the Kober lab focuses on understanding how enzymatic functions are regulated. We take highly interdisciplinary approaches and primarily focus on the mechanisms of protein homeostasis in the context of lipid metabolism.

Meet the Krishnan Lab team.

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In vivo drug distribution dynamics in thermoablated and normal rabbit livers from biodegradable polymers Jinming Gao,1 Feng Qian,1 Agata Szymanski-Exner,1 Nicholas Stowe,2 John Haaga3 1Cancer-Targeted Drug Delivery Laboratory, Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 2Department of Surgery, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106 3Department of Radiology, University Hospitals of Cleveland, Cleveland, Ohio

2013;12:2110-2120. Published OnlineFirst July 24, 2013.Mol Cancer Ther    Erik A. Bey, Kathryn E. Reinicke, Melissa C. Srougi, et al.   Directed Programmed Necrosis in NQO1-Positive Breast Cancers −Induced PARP1 Hyperactivation−-LapachoneβCatalase Abrogates   Updated version   10.1158/1535-7163.MCT-12-0962doi: Access the most recent version of this article at:   Material Supplementary   http://mct.aacrjournals.org/content/suppl/2013/07/24/1535-7163.MCT-12-0962.DC1.html Access

Learn about the Krishnan Lab's research.