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Imaging Agents DOI: 10.1002/anie.201301135 Multi-Chromatic pH-Activatable 19F-MRI Nanoprobes with Binary ON/OFF pH Transitions and Chemical-Shift Barcodes** Xiaonan Huang, Gang Huang, Shanrong Zhang, Koji Sagiyama, Osamu Togao, Xinpeng Ma, Yiguang Wang, Yang Li, Todd C. Soesbe, Baran D. Sumer, Masaya Takahashi, A. Dean Sherry, and Jinming Gao* Magnetic resonance imaging (MRI) is a powerful non- invasive imaging technique that has greatly impacted basic biological research as well clinical

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim www.advhealthmat.de www.MaterialsViews.com wileyonlinelibrary.com 1 C O M M U N IC A TIO N Prodrug Strategy to Achieve Lyophilizable, High Drug Loading Micelle Formulations Through Diester Derivatives of β-Lapachone Xinpeng Ma , Xiumei Huang , Gang Huang , Longshan Li , Yiguang Wang , Xiuquan Luo , David A. Boothman , and

The Laryngoscope VC 2014 The American Laryngological, Rhinological and Otological Society, Inc. In Vivo Optical Imaging of Folate Receptor-b in Head and Neck Squamous Cell Carcinoma Joel Y. Sun, BA; Jiayin Shen, PhD; Joel Thibodeaux, MD; Gang Huang, PhD; Yiguang Wang, PhD; Jinming Gao, PhD; Philip S. Low, PhD; Dimiter S. Dimitrov, PhD; Baran D. Sumer, MD Objectives/Hypothesis: Folate receptor (FR) expression, although known to be elevated in many types of cancer and inflammatory cells, has

MRI-Visible Micellar Nanomedicine for Targeted Drug Delivery to Lung Cancer Cells Jagadeesh Setti Guthi,†,‡ Su-Geun Yang,†,‡ Gang Huang,† Shunzi Li,†,§ Chalermchai Khemtong,† Chase W. Kessinger,† Michael Peyton,†,| John D. Minna,†,§,| Kathlynn C. Brown†,§, and Jinming Gao*,† Department of Pharmacology, Simmons ComprehensiVe Cancer Center, Department of Internal Medicine, DiVision of Translational Research, and Hamon Center for Therapeutic Oncology Research, UniVersity of Texas Southwestern

ORIGINAL RESEARCH Preliminary NSQIP results: A tool for quality improvement 26 Stachler et al Cost analysis of intubation-related tracheal injury using a national database 31 Bhatti et al Wrong-site sinus surgery in otolaryngology 37 Shah et al Bipolar radiofrequency tonsillotomy compared with traditional cold dissection tonsillectomy in adults with recurrent tonsillitis 42 Nemati et al Clinical consensus statement: Diagnosis and management of nasal valve compromise 48 Rhee et al Nasal septum to

communications 1632 Nanoimprint lithography Fabrication of Polymeric Nanorods Using Bilayer Nanoimprint Lithography** Fatih Buyukserin, Mukti Aryal, Jinming Gao, and Wenchuang Hu* Polymeric nanoparticles are becoming increasingly important in a variety of biological applications, such as biomolecular sensing, diagnostic imaging, and therapeutic drug delivery.[1,2] For these applications, the mass production of multifunctional nanocomposite materials with precise control of particle size

Author's personal copy Off-resonance saturation MRI of superparamagnetic nanoprobes: Theoretical models and experimental validations Chalermchai Khemtong a, Osamu Togao b, Jimin Ren b, Chase W. Kessinger a, Masaya Takahashi b, A. Dean Sherry b, Jinming Gao a,⇑ a Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, United States b The Advanced Imaging Research Center, University

Journal of Controlled Release 151 (2011) 271–277 Contents lists available at ScienceDirect Journal of Controlled Release j ourna l homepage: www.e lsev ie r.com/ locate / jconre l N A N O M E D IC IN E Nanoscopic micelle delivery improves the photophysical properties and efficacy of photodynamic therapy of protoporphyrin IX Huiying Ding a, Baran D. Sumer c, Chase W. Kessinger a, Ying Dong a,b, Gang Huang a, David A. Boothman a,b, Jinming Gao a,⁎ a Department of Pharmacology, University of

YU ET AL . VOL. 5 ’ NO. 11 ’ 9246–9255 ’ 2011 www.acsnano.org 9246 October 19, 2011 C 2011 American Chemical Society Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery Haijun Yu,† Yonglong Zou,†,‡ Yiguang Wang,† Xiaonan Huang,† Gang Huang,† Baran D. Sumer,§ David A. Boothman,†,‡ and Jinming Gao†,* †Department of Pharmacology, ‡Department of Radiation Oncology, and §Department of Otolaryngology, Simmons Comprehensive Cancer

Journal of Controlled Release 156 (2011) 276–280 Contents lists available at SciVerse ScienceDirect Journal of Controlled Release j ourna l homepage: www.e lsev ie r .com/ locate / jconre l Concept paper Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia Huiying Ding a, Haijun Yu a, Ying Dong a, Ruhai Tian a, Gang Huang a, David A. Boothman a, Baran D. Sumer b, Jinming Gao a,⁎ a Department of