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Zhijian “James” Chen Elected to the Fellowship of the Royal Society.

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Skip to main content Mechanism and Regulation of Ribosome Biogenesis Ribosome biogenesis is one of the most intricate and energy-intensive processes in the cell. In our lab, we investigate how the large ribosomal subunit (60S) is assembled from RNA and proteins through a finely tuned series of enzymatic and structural events, mapping these processes at molecular resolution to reveal their order, timing, coordination, and regulation. Our focus is on the molecular machines, such as ATPases and

The Drapkin Lab investigates the molecular drivers of oncogenesis, metastasis, and chemoresistance in small cell lung cancer (SCLC) to discover new therapeutic targets. 

Skip to main content Contact Us Contact Information Dr Robert Tower UT Southwestern Medical Center 6000 Harry Hines Blvd. Dallas, TX, 75235 Email

Skip to main content Publications Content Research Publication (last 3 years) Yun, E.J., Zhou, J., Lin, C-H., Hernandez, E., Fazli, L., Gleave,, Hsieh, J.T. (2016) Targeting cancer stem cell in castration resistant prostate cancer. Clin. Cancer Res., 22:670-679. PMID26876207 Zhou, J.C., Zhu, G., Huang, J., Li, L., Du, Y., Gao, Y., Wu, D., Wang, X., Hsieh, J.T., He, D., Wu K. (2016) Non-canonical GLI1/2 activation by PI3K/AKT signaling in renal cell carcinoma: A novel potential therapeutic target

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