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Correlation between the Charge of Proteins in Solution and in the Gas Phase Investigated by Protein Charge Ladders, Capillary Electrophoresis, and Electrospray Ionization Mass Spectrometry Jeffrey D. Carbeck,† Joanne C. Severs,‡ Jinming Gao,† Qinyuan Wu,‡ Richard D. Smith,* ,‡ and George M. Whitesides*,† Department of Chemistry and Chemical Biology, HarVard UniVersity, 12 Oxford Street, Cambridge, Massachusetts 02138, and EnVironmental Molecular Science Laboratory, Pacific Northwest National

Get to know our Principal Investigator and team of researchers at Waugh Lab.   

COMMUNICATIONS Surface Modification of Polyanhydride Microspheres JINMING GAO†,‡, LAURA NIKLASON†,‡, XIAO-MEI ZHAO§, AND ROBERT LANGER*,† Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, Department of Anesthesia, Massachusetts General Hospital, Boston, Massachusetts 02114, and Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138 Received July 25, 1997. Final revised manuscript received

The goal of our Basic Science projects is to build anatomical knowledge of the Human Brain

If you're interested in joining our team, please reach out to learn more about open positions.  

In addition to our work on mechanisms of FMRP function at synapses, we have also contributed to the understanding of circuit dysfunction in Fragile X Syndrome, with a goal to reveal mechanisms of FMRP function in the brain, but also to identify therapeutic targets to correct and restore circuit

Publications of Psychoneuroendocrine Research Lab

The Huber lab is focused on understanding how activity-regulated transcription and translation in neurons controls synapse and circuit plasticity and development. 

To mediate long-term changes in function and structure of such numerous contacts, somewhat independently, neurons utilize “localized” protein synthesis within dendrites and near synapses.

Subscriber access provided by UNIV TEXAS SW MEDICAL CENTER Journal of the American Chemical Society is published by the American Chemical Society. 1155 Sixteenth Street N.W., Washington, DC 20036 Using Electrospray Ionization FTICR Mass Spectrometry To Study Competitive Binding of Inhibitors to Carbonic Anhydrase Xueheng Cheng, Ruidan Chen, James E. Bruce, Brenda L. Schwartz, Gordon A. Anderson, Steven A. Hofstadler, David C. Gale, Richard D. Smith, Jinming Gao, George B. Sigal, Mathai Mammen