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ARTICLE Received 23 May 2016 | Accepted 13 Sep 2016 | Published 27 Oct 2016 Molecular basis of cooperativity in pH-triggered supramolecular self-assembly Yang Li1, Tian Zhao1, Chensu Wang1,2, Zhiqiang Lin1, Gang Huang1, Baran D. Sumer3 & Jinming Gao1 Supramolecular self-assembly offers a powerful strategy to produce high-performance, stimuli-responsive nanomaterials. However, lack of molecular understanding of stimulated responses frequently hampers our ability to rationally design

CANCER RESEARCH | MOLECULAR CELL BIOLOGY HIF2-Induced Long Noncoding RNA RAB11B-AS1 Promotes Hypoxia-Mediated Angiogenesis and Breast Cancer Metastasis Yanling Niu1, Lei Bao1, Yan Chen1, ChenliangWang1, Maowu Luo1, Bo Zhang1, Mi Zhou1, Jennifer E. Wang1, Yisheng V. Fang1, Ashwani Kumar2, Chao Xing2,3,4, Yingfei Wang1,5, and Weibo Luo1,6 ABSTRACT ◥ Hypoxia induces a vast array of long noncoding RNAs (lncRNA) in breast cancer cells, but their biological functions remain largely unknown. Here

ARTICLES PUBLISHED ONLINE: 8 DECEMBER 2013 | DOI: 10.1038/NMAT3819 A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals Yiguang Wang1, Kejin Zhou1, Gang Huang1, Christopher Hensley2, Xiaonan Huang1, Xinpeng Ma1, Tian Zhao1, Baran D. Sumer3, Ralph J. DeBerardinis2 and Jinming Gao1* Stimuli-responsive nanomaterials are increasingly important in a variety of applications such as biosensing, molecular imaging, drug

Zhongzheng (Brooks) Fu, Ph.D. Last updated: September, 2023 ORCID: 0000-0002-2572-6284 Email: zhongzheng.fu@utsouthwestern.edu Website: zfu-lab.org 5323 Harry Hines Blvd, MC 8855 Dallas, TX 75390 United States Academic Positions 2023 – on Assistant Professor Department of Neurological Surgery UT Southwestern Medical Center Dallas, TX, USA 2023 – on Visiting Scholar Division of the Humanities and Social Sciences California Institute of Technology Pasadena, CA, USA Postdoctoral Trainings

\ PEGSITACIANINE FOR THE SURGICAL DETECTION OF HEAD AND NECK CANCER PURPOSE INCLUSION DESIGN To investigate whether Pegsitacianine a fluorescent nanoparticle can image head and neck cancer and unknown primary head and neck cancer during surgery or biopsy. 1. Adults ≥ 18 years of age 2. Patients with stage 1-4 Head and Neck Squamous Cell Carcinoma (HNSCC) undergoing surgical excision 1. Phase 2 Clinical trial of Pegsitacianine, which is

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