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We are interested in building small organic molecules and studying their functions in biological systems. Our lab started in 2004 using state-of-the-art tools to address challenging issues in the field of natural product synthesis. 

Get to know our Principal Investigator and team of researchers at Boyuan Wang Lab  

Original Investigations Quantitative Computed Tomography Analysis of Local Chemotherapy in Liver Tissue After Radiofrequency Ablation1 Agata A. Exner, PhD, Brent D. Weinberg, BS, Nicholas T. Stowe, PhD, Anthony Gallacher, MS, David L. Wilson, PhD, John R. Haaga, MD, Jinming Gao, PhD Rationale and Objectives. Computed tomography (CT) was used to noninvasively monitor local drug pharmacokinetics from polymer implants in rat livers before and following radiofrequency ablation. Materials and

The Wang Lab uses chemical biology tools to study the molecular mechanisms underlying interesting bacterial behaviors.

If you're interested in joining our team, please reach out to learn more about open positions at Alto Lab.

Learn about Kittler Lab's research.

Development of B-Lapachone Prodrugs forTherapyAgainst Human Cancer Cells with Elevated NAD(P)H:Quinone Oxidoreductase1Levels Kathryn E. Reinicke,1,2 Erik A. Bey,1,3 Melissa S. Bentle,1,4 JohnJ. Pink,1,3 Stephen T. Ingalls,4,6 Charles L. Hoppel,4,6,7 Rosana I. Misico,8 GiselaM. Arzac,8 Gerardo Burton,8William G. Bornmann,9 Damon Sutton,5 Jinming Gao,5 and David A. Boothman1,3,4 Abstract B-Lapachone, an o-naphthoquinone, induces a novel caspase- and p53-independent apoptotic

www.elsevier.com/locate/jconrel Journal of Controlled Release 98 (2004) 415–426 Micellar carriers based on block copolymers of poly(q-caprolactone) and poly(ethylene glycol) for doxorubicin delivery Xintao Shuaia,1, Hua Aia,1, Norased Nasongklab, Saejeong Kima, Jinming Gaoa,* aDepartment of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA bDepartment of Macromolecular Science and Engineering, Case Western Reserve University, 10900 Euclid

Doxorubicin and b-Lapachone Release and Interaction with Micellar Core Materials: Experiment and Modeling DAMON SUTTON,*,� SHIHU WANG,� NORASED NASONGKLA,*,�,1 JINMING GAO,* AND ELENA E. DORMIDONTOVA�,2 *Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390; and �Department of Macromolecular Science and Engineering, Case Western Reserve University, Cleveland, Ohio 44106 Polymer micelles with two different core-forming blocks, poly(D,L

Meet the Kittler Lab team.