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Journal of Controlled Release 83 (2002) 415–425 www.elsevier.com/ locate/ jconrel N oninvasive monitoring of local drug release in a rabbit radiofrequency (RF) ablation model using X-ray computed tomography a b a aAgata Szymanski-Exner , Nicholas T. Stowe , Roee S. Lazebnik , Kyle Salem , a c a,c ,*David L. Wilson , John R. Haaga , Jinming Gao aDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106,USA bDepartment of Surgery, Case Western Reserve

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Publications for Boyuan Wang, Ph.D.

Antitumor efficacy and local distribution of doxorubicin via intratumoral delivery from polymer millirods Brent D. Weinberg,1 Hua Ai,2 Elvin Blanco,3 James M. Anderson,4 Jinming Gao3 1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 2National Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China 3Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, Texas 75390 4Institute of Pathology

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Effect of fibrous capsule formation on doxorubicin distribution in radiofrequency ablated rat livers Elvin Blanco,1 Feng Qian,1 Brent Weinberg,1 Nicholas Stowe,2 James M. Anderson,3 Jinming Gao1 1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio 44106 2Department of Surgery, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106 3Institute of Pathology, University Hospitals of Cleveland, Cleveland, Ohio 44106 Received 24 October 2003

Riboswitches – short segments of mRNA that bind to small molecules and cause a change in expression of proteins coded by the RNA – allows protein expression to self-regulate.

©2 005 LA ND ES BIO SCI EN CE. DO NO T D IST RIB UT E. [Cancer Biology & Therapy 4:1, 95-102, January 2005]; ©2005 Landes Bioscience Matthew Ough4 Anne Lewis4 Erik A. Bey6 Jinming Gao6 Justine M. Ritchie3 William Bornmann7 David A. Boothman6 Larry W. Oberley2,3,4 Joseph J. Cullen1,2,3,4,5,* Departments of 1Surgery, 2Radiation Oncology and the 3Holden Comprehensive Cancer Center; 4University of Iowa College of Medicine; Iowa City, Iowa USA 5Veterans Affairs Medical Center; Iowa

Comparison of Doxorubicin Concentration Profiles in Radiofrequency-Ablated Rat Livers from Sustained- and Dual-Release PLGA Millirods Feng Qian,1,4 Nicholas Stowe,2 Gerald M. Saidel,1 and Jinming Gao1,3 Received November 7, 2003; accepted November 18, 2003 Purpose. To evaluate and compare the local pharmacokinetics of doxorubicin in radiofrequency (rf)-ablated rat livers after interstitial delivery from sustained- and dual-release poly(D,L-lactide-co-glyco- lide) (PLGA) millirods. Methods