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© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim www.advhealthmat.de www.MaterialsViews.com wileyonlinelibrary.com 1 C O M M U N IC A TIO N Prodrug Strategy to Achieve Lyophilizable, High Drug Loading Micelle Formulations Through Diester Derivatives of β-Lapachone Xinpeng Ma , Xiumei Huang , Gang Huang , Longshan Li , Yiguang Wang , Xiuquan Luo , David A. Boothman , and

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β‑Lapachone and Paclitaxel Combination Micelles with Improved Drug Encapsulation and Therapeutic Synergy as Novel Nanotherapeutics for NQO1-Targeted Cancer Therapy Ling Zhang,† Zhen Chen,† Kuan Yang,† Chun Liu,† Jinming Gao,‡ and Feng Qian*,† †Department of Pharmacology and Pharmaceutical Sciences and Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, School of Medicine, Tsinghua University, Beijing 100084, P.R. China ‡Simmons Comprehensive Cancer Center

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German Edition: DOI: 10.1002/ange.201610302Drug Delivery International Edition: DOI: 10.1002/anie.201610302 A Redox-Activatable Fluorescent Sensor for the High-Throughput Quantification of Cytosolic Delivery of Macromolecules Zhaohui Wang+, Min Luo+, Chengqiong Mao, Qi Wei, Tian Zhao, Yang Li, Gang Huang, and Jinming Gao* Abstract: Efficient delivery of biomacromolecules (e.g., proteins, nucleic acids) into cell cytosol remains a critical challenge for the development of macromolecular

Skip to main content Blue Steel Program Mood Disorders Research Promoting Mental Health and Resilience Resilience and risk factors related to depression in young adults is not well understood and addressing mental illness in this population will not only require screening and treatment, but also early intervention and prevention for those at risk. Particularly, little is known about how to build resilience, which is an interactive process that occurs as a result of life events, individual

Journal of Controlled Release 151 (2011) 271–277 Contents lists available at ScienceDirect Journal of Controlled Release j ourna l homepage: www.e lsev ie r.com/ locate / jconre l N A N O M E D IC IN E Nanoscopic micelle delivery improves the photophysical properties and efficacy of photodynamic therapy of protoporphyrin IX Huiying Ding a, Baran D. Sumer c, Chase W. Kessinger a, Ying Dong a,b, Gang Huang a, David A. Boothman a,b, Jinming Gao a,⁎ a Department of Pharmacology, University of

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2013;12:2110-2120. Published OnlineFirst July 24, 2013.Mol Cancer Ther    Erik A. Bey, Kathryn E. Reinicke, Melissa C. Srougi, et al.   Directed Programmed Necrosis in NQO1-Positive Breast Cancers −Induced PARP1 Hyperactivation−-LapachoneβCatalase Abrogates   Updated version   10.1158/1535-7163.MCT-12-0962doi: Access the most recent version of this article at:   Material Supplementary   http://mct.aacrjournals.org/content/suppl/2013/07/24/1535-7163.MCT-12-0962.DC1.html Access

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