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Publications Content for Cozen Lab.

1 Ready; Catalysis Hydrogenation Categories and Dichotomies: Heterogeneous or Homogeneous Neutral or Cationic Directed or Non-directed Heterolytic or Homolytic H2 Activation Racemic or Enantioselective Syn or Trans Addition Homogeneous Hydrogenation Rh Ph3P Ph3P Cl PPh3 Advantages: Mild conditions Improved selectivity Directed Hydrogenation Enantioselective Hydrogenation Mechanistically accessible Disadvantages: Purification $$$$ Often less

Wakeland Lab's Administration

#!/usr/bin/perl     open(FILE1,  "Input.fastq")  or  die("Unable  to  open  file");   open(OUTPUT,  ">Output.fastq")  or  die("Unable  to  open  file");   use  strict;     my  $line;   my  @line;   my  $line1;   my  $seq0;   my  $junk;   my  $qual0;   my  $qual;   my  $seq;   my  $base;   my  $rest;   my  $newline;   my  @newline;   my  $n=1;   my  $m=1;   my  $newscore;   my  $restscore;   my

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Minimal Residual Disease and Metastasis Postdoctoral positions are available in the laboratory of Dr. Srinivas Malladi, Ph.D. - Faculty Profile - UT Southwestern, Department of Pathology at UT Southwestern Medical Center to study the biology of minimal residual disease and metastasis in breast, lung and renal Adenocarcinomas. Malladi Lab - UT Southwestern, Dallas, Texas is focused on understanding how disseminated cancer cells survive, evade immune surveillance and give rise to overt

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We focus on the discovery of targeted therapies for major drivers of cancer using protein chemistry, enzymology, structural biology, informatics and cell biology. Some of our favorite targets are RAS and kinase proteins.

In prior work, my laboratory focused on identifying novel mechanisms of therapy-resistance and progression in breast, prostate and ovarian cancer. 

Ready; Catalysis Isomerization/cyclization-1 R M R' M R R' H R R' M H MH R R' H R' M M H Olefin insertion into Metal alkyl can be followed by hydride elimination or additional olefin insertions: -dimerization/oligomerization -small molecules -polymerization Recall: electron rich M (late transition metal) Keq < 1 ->dimerization, etc electron poor M (early transition metal) Keq > 1 ->polymerization P Ph2 Ni OO H C7-C14 C1-C3 HO C10-C18 C1-C3 C7-C14 Shell