U N C O R R E C TE D P R O O F Please cite this article in press as: Chen, H. et al., Nanonization strategies for poorly water-soluble drugs, Drug Discov Today (2010), doi:10.1016/j.drudis.2010.02.009 Drug Discovery Today � Volume 00, Number 00 �March 2010 REVIEWS Nanonization strategies for poorly water-soluble drugs Huabing Chen1, Chalermchai Khemtong1, Xiangliang Yang2, Xueling Chang3 and Jinming Gao1 1Department of Pharmacology, Harold C. Simmons Comprehensive Cancer Center

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Modeling Particle Shape-Dependent Dynamics in Nanomedicine Samar Shah1, Yaling Liu2,*, Walter Hu3, and Jinming Gao4 1 Department of Mechanical and Aerospace Engineering, The University of Texas at Arlington, Arlington, Texas, 76019 2 Department of Mechanical Engineering and Mechanics, Bioengineering Program, Lehigh University, Bethlehem, PA 18015 USA 3 Department of Electrical Engineering, The University of Texas at Dallas, Richardson, TX 75080 4 Department of Pharmacology, Harold C. Simmons

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