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The Center for Depression Research and Clinical Care (CDRC) is nationally recognized for its cutting-edge research in unipolar and bipolar depression. The research conducted within the center brings better understanding of the causes of depression, identifies effective new treatments, and improves

RESEARCH ON SYMPTOM MONITORING AND PREVENTIVE COGNITIVE THERAPY FOR PERINATAL DEPRESSION The Department of Psychiatry at the University of Texas Southwestern Medical Center is conducting research sponsored by the National Institute of Mental Health (NIMH) on perinatal depression, aiming to develop a treatment program for conceiving or pregnant women at risk for depressive relapse and recurrence. We are recruiting women with a history of depression who are planning to become

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Mitral Valve Phase Contrast Imaging Is a More Reproducible Method of Determining Cardiac Rest Periods for Whole-Heart Coronary Magnetic Resonance Angiography in Congenital Heart Disease than 4 Chamber Cine. Maria Batsis, MD; F. Gerald Greil, MD, PhD; Animesh Tandon, MD, MS; Tarique Hussain, MD, PhD University of Texas Southwestern Medical Center, Dallas, TX, USA; Children’s Medical Center of Dallas Background Whole heart coronary magnetic resonance angiography (CMRA) offers detailed

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Aortic Vessel Wall Imaging Using 3D Phase Sensitive Inversion Recovery in Children and Young Adults Animesh Tandon, MD, MS1,2, Tarique Hussain, MD, PhD1,2, Andrew Tran, MD, MS3, René M Botnar, PhD4, Gerald F Greil, MD, PhD1,2, and Markus Henningsson, PhD4 1Pediatrics, Radiology, BME, University of Texas Southwestern Medical Center, Dallas, TX, USA 2Pediatric Cardiology, Children's Medical Center Dallas, Dallas, TX, USA 3Pediatrics, University of Texas Southwestern Medical Center, Dallas

Probing the Energetics of Dissociation of Carbonic Anhydrase-Ligand Complexes in the Gas Phase Jinming Gao,* Qinyuan (Quincey) Wu,# Jeffrey Carbeck,* Q. Paula Lei,# Richard D. Smith,# and George M. Whitesides* *Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, and #Environmental Molecular Science Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352 USA ABSTRACT This paper describes the use of electrospray ionization

Reductions General Resource: Trost, Comp. Org. Syn. 1991, vol 8 March,1992, chap 19 Carey and Sundberg, vol B, Chap 5 Smith, Organic Synthesis, Chap 4 Material organized (roughly) by transformation From March, 1992, p1208 H H Two general classes: Transition metal hydrogenation and dissolving metal reduction Hydrogenation: Covered in much more detail in Advanced Synthesis and Catalysis. H HM H2 General trends: more substituted = slower relationship of pressure:rate often not simple

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Oxidation of Unsaturated Systems 2 general reactivity patterns: X H X Yn+2 X+ Yn ++ OH simple example O A- Me2SCl+ S+ O + S + Cl- 2 electron oxidation 1 electron oxidation Xor -1 e- or X we will focus on oxidation of aromatic rings and enol/enolate systems Couple Eo Fe(III) + e- Fe(II) 0.77 V(V) + e- V(IV) 1.00 Tl(III) + 2 e- Th(I) 1.25 Pb(IV) + 2 e- Pb(II) 1.6-1.7 Mn(III) + e- 1.56Mn(II) Ce(IV) + e- Ce(III) 1.6 Reduction potentials of oxidants we will look at (bigger number