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A transistor-like pH nanoprobe for tumour detection and image-guided surgery
https://labs.utsouthwestern.edu/sites/default/files/2022-11/115_Zhao_NatBME.pdf
NATURE BIOMEDICAL ENGINEERING 1, 0006 (2016) | DOI: 10.1038/s41551-016-0006 | www.nature.com/natbiomedeng 1 ARTICLES PUBLISHED: 19 DECEMBER 2016 | VOLUME: 1 | ARTICLE NUMBER: 0006 A transistor-like pH nanoprobe for tumour detection and image-guided surgery Tian Zhao1†, Gang Huang1, Yang Li1, Shunchun Yang1, Saleh Ramezani2, Zhiqiang Lin1, Yiguang Wang1, Xinpeng Ma1, Zhiqun Zeng1, Min Luo1, Esther de Boer3, Xian-Jin Xie4, Joel Thibodeaux5, Rolf A. Brekken6, Xiankai Sun2, Baran D. Sumer7
Microsoft Word - FACLR_Human_iPSCs_SOP_2025.docx
https://labs.utsouthwestern.edu/sites/default/files/2025-05/FACLR_Human_iPSCs_SOP_2025.pdf
1 updated May 2025 Napierala Lab protocol for culturing human iPSCs For additional details and recommendations, please refer to “Maintenance of Human Pluripotent Stem Cells in mTeSRTM Plus” Technical Manual (STEMCELL Technologies). Necessary Reagents Reagent Company Catalog Number Corning™ Matrigel™ hESC-Qualified Matrix Fisher Scientific 08-774-552 mTeSRTM Plus Complete Kit STEMCELL Technologies 100-0276 CryoStor® CS10 STEMCELL Technologies 07930 Dispase 1U/mL, 100mL
Lipid Reprogramming | Corbin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/corbin-lab/research/metabolic-hallmarks-cancer/lipid-reprogramming
Development and progression of cancer are frequently associated with altered rates of lipid synthesis, mobilization and metabolism in tumor cells.
Microsoft Word - FACLR_iPSC_05_2025_JSN.docx
https://labs.utsouthwestern.edu/sites/default/files/2025-05/FACLR_iPSC_lines_2025_0.pdf
1 updated May 2025 Sendai virus reprogrammed iPSC Lines * Clone used for CRISPR/Cas9 editing of GAA repeats Line Clone # Sex GAA repeat number in fibroblasts GAA repeat number in iPSCs Karyotype data Karyotype passage CTRL 3348 6 M Control size Control size Yes, normal p11 CTRL 7522 5 F Control size Control size Yes, normal p15 CTRL 7522 12 F Control size Control size Yes, normal p13 CTRL 6718 1 M Control size Control size Yes, normal p4 CTRL 6718 6 M
Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation
https://labs.utsouthwestern.edu/sites/default/files/2022-07/41598_2018_Article_22819.pdf
1Scientific RePorTS | (2018) 8:4501 | DOI:10.1038/s41598-018-22819-3 www.nature.com/scientificreports Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation Antoine Abou-Jaoude1, Lise Badiqué1, Mohamed Mlih1, Sara Awan1, Sunning Guo1, Alexandre Lemle1, Clauda Abboud1, Sophie Foppolo1, Lionel Host1, Jérôme Terrand1, Hélène Justiniano1, Joachim Herz2, Rachel L. Matz1 & Philippe Boucher 1
Polyvalent design in the cGAS-STING pathway
https://labs.utsouthwestern.edu/sites/default/files/2022-11/135_Bennett_SIM.pdf
Seminars in Immunology xxx (xxxx) xxx Please cite this article as: Zachary T. Bennett, Seminars in Immunology, https://doi.org/10.1016/j.smim.2021.101580 1044-5323/© 2021 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Polyvalent design in the cGAS-STING pathway Zachary T. Bennett a, Suxin Li a, Baran D. Sumer b, Jinming Gao a,b,c,* a Department of Pharmacology, Harold C. Simmons
Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial adhesion and lesion macrophage accumulation
https://labs.utsouthwestern.edu/sites/default/files/2022-07/nihms814446.pdf
Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial adhesion and lesion macrophage accumulation Yinyuan Ding1,2,3,*, Linzhang Huang4,*, Xunde Xian1,2,*, Ivan S. Yuhanna4, Catherine R. Wasser1,2, Michael Frotscher5, Chieko Mineo4, Philip W. Shaul4,†, and Joachim Herz1,2,6,7,8,† 1Department of Molecular Genetics, UT Southwestern Medical Center, Dallas, TX 75390, USA. 2Center for Translational Neurodegeneration Research, UT Southwestern Medical Center, Dallas
People | Mootha Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/mootha-lab/people
Meet the Mootha Lab team.
Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF–RANKL signaling
https://labs.utsouthwestern.edu/sites/default/files/2022-07/41413_2017_Article_6.pdf
ARTICLE OPEN Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF–RANKL signaling Alexander Bartelt1,2,8, Friederike Behler-Janbeck1,2, F. Timo Beil1,3, Till Koehne3,4, Brigitte Müller1,2, Tobias Schmidt1,2, Markus Heine2,5, Laura Ochs1,2, Tayfun Yilmaz3, Martin Dietrich6, Jan P. Tuckermann7, Michael Amling3, Joachim Herz6, Thorsten Schinke3, Joerg Heeren2 and Andreas Niemeier1,2 Skeletal health relies on architectural integrity and sufficient
Image Guided Drug Delivery | Corbin Lab | UT Southwestern, Dallas, Texas
https://labs.utsouthwestern.edu/corbin-lab/research/image-guided-drug-delivery
Primarily located in the Advanced Imaging Research Center the Corbin Lab routinely utilizes state-of-the–art small animal imaging systems (MRI, micro-MRI, Optical, micro-CT/SPECT/PET) to characterize rodent models of disease.