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Real time X-ray imaging is performed to facilitate loco-regional delivery of nanotherapies to tumors. This technique is primarily used for the treatment of liver tumors.

Chung Lab publications

Selected publications of Herz Lab

Meet the Chung Lab team

Herz Lab publications

Skip to main content Join Us Become a Team Member The Whitehurst lab is seeking energetic, dedicated graduate students and postdoctoral fellows to join our work. Current Projects Cancer-Testis Antigens (aka Cancer Germline Genes) Cancer-testis antigens are normally only expressed in testis, but we have discovered a cohort of cancer-testis antigens expressed in tumor cells and localized to the mitochondria. Inhibition of these proteins leads to a loss of tumor cell viability. This project will

Ready; Catalysis Conjugate Addition Topics covered 1. 1,4 addition involving copper a. stoichiometric reactions b. catalytic reactions c. allylic substitution 2. Conjugate addition without copper a. Ni-based systems b. Rh-based systems 3. Catalytic addition of heteroatoms Topics not covered: enolate conjugate additions, Friedel-Crafts-type conjugate additions Ready; Catalysis Conjugate Addition: origin 1,4 addition reactions involving

Chen (Zhijian "James") Lab publications

Reductions General Resource: Trost, Comp. Org. Syn. 1991, vol 8 March,1992, chap 19 Carey and Sundberg, vol B, Chap 5 Smith, Organic Synthesis, Chap 4 Material organized (roughly) by transformation From March, 1992, p1208 H H Two general classes: Transition metal hydrogenation and dissolving metal reduction Hydrogenation: Covered in much more detail in Advanced Synthesis and Catalysis. H HM H2 General trends: more substituted = slower relationship of pressure:rate often not simple

Skip to main content Research The Whitehurst Lab uses RNAi-based functional genomics to identify gene products that support viability and/or modulate chemotherapeutic sensitivity in tumor cells. Using this strategy, we discovered that tumor cells can depend on aberrantly activated gametogenic genes for survival. Activation of gametogenic genes is a hallmark of cancer Tumors frequently express genes that are otherwise restricted to gametogenic tissues, including the ovary, placenta, and testis