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Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning Catherine R. Wasser1,2,*,>†, Irene Masiulis2,†, Murat S. Durakoglugil1,2, Courtney Lane- Donovan1,2, Xunde Xian1,2, Uwe Beffert2, Anandita Agarwala2, Robert E. Hammer3, and Joachim Herz1,2,4,5,* 1Center for Translational Neurodegeneration Research, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA 2Department of Molecular Genetics, University of Texas Southwestern Medical

Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial adhesion and lesion macrophage accumulation Yinyuan Ding1,2,3,*, Linzhang Huang4,*, Xunde Xian1,2,*, Ivan S. Yuhanna4, Catherine R. Wasser1,2, Michael Frotscher5, Chieko Mineo4, Philip W. Shaul4,†, and Joachim Herz1,2,6,7,8,† 1Department of Molecular Genetics, UT Southwestern Medical Center, Dallas, TX 75390, USA. 2Center for Translational Neurodegeneration Research, UT Southwestern Medical Center, Dallas

1Scientific RePorTS | (2018) 8:4501 | DOI:10.1038/s41598-018-22819-3 www.nature.com/scientificreports Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation Antoine Abou-Jaoude1, Lise Badiqué1, Mohamed Mlih1, Sara Awan1, Sunning Guo1, Alexandre Lemle1, Clauda Abboud1, Sophie Foppolo1, Lionel Host1, Jérôme Terrand1, Hélène Justiniano1, Joachim Herz2, Rachel L. Matz1 & Philippe Boucher   1

1 updated May 2025 Sendai virus reprogrammed iPSC Lines * Clone used for CRISPR/Cas9 editing of GAA repeats Line Clone # Sex GAA repeat number in fibroblasts GAA repeat number in iPSCs Karyotype data Karyotype passage CTRL 3348 6 M Control size Control size Yes, normal p11 CTRL 7522 5 F Control size Control size Yes, normal p15 CTRL 7522 12 F Control size Control size Yes, normal p13 CTRL 6718 1 M Control size Control size Yes, normal p4 CTRL 6718 6 M

Structural Biology and Biochemistry of Gene Regulation A joint postdoctoral training position is available in the laboratories of Dr. W. Lee Kraus and Dr. Xin Liu in the Cecil H. and Ida Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center to study signaling and gene regulation and molecular biophysics of gene regulation. We are seeking a trainee interested in studying gene regulatory complexes, who will initiate and execute research projects

CURRICULUM VITAE Jef Karel De Brabander, Ph.D. Department of Biochemistry, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., Dallas, TX-75390-9038 Voice: (214) 648-7808, Fax: (214) 648-0320, E-mail: jef.debrabander@utsouthwestern.edu Education December 1993 Ph.D. in Chemistry (Highest Honors), University of Gent, Belgium July 1987 B.Sc. in Chemistry (Distinction), University of Gent, Belgium Professional Experience 2011- Julie and Louis

Harold C. Simmons Comprehensive Cancer Center Bioinformatics Data Science Shared Resource Data Science Fellowship Agreement SCCC-DSSR This agreement is between the parties named below and the Director of SCCC-DSSR, Professor Jeon Lee. By signing this document, awardees (and their mentors, if applicable) acknowledge and agree to abide by the fellowship conditions listed below. Fellowship Awardee (Full Name

Mitral Valve Phase Contrast Imaging Is a More Reproducible Method of Determining Cardiac Rest Periods for Whole-Heart Coronary Magnetic Resonance Angiography in Congenital Heart Disease than 4 Chamber Cine. Maria Batsis, MD; F. Gerald Greil, MD, PhD; Animesh Tandon, MD, MS; Tarique Hussain, MD, PhD University of Texas Southwestern Medical Center, Dallas, TX, USA; Children’s Medical Center of Dallas Background Whole heart coronary magnetic resonance angiography (CMRA) offers detailed

Aortic Vessel Wall Imaging Using 3D Phase Sensitive Inversion Recovery in Children and Young Adults Animesh Tandon, MD, MS1,2, Tarique Hussain, MD, PhD1,2, Andrew Tran, MD, MS3, René M Botnar, PhD4, Gerald F Greil, MD, PhD1,2, and Markus Henningsson, PhD4 1Pediatrics, Radiology, BME, University of Texas Southwestern Medical Center, Dallas, TX, USA 2Pediatric Cardiology, Children's Medical Center Dallas, Dallas, TX, USA 3Pediatrics, University of Texas Southwestern Medical Center, Dallas

Reductions General Resource: Trost, Comp. Org. Syn. 1991, vol 8 March,1992, chap 19 Carey and Sundberg, vol B, Chap 5 Smith, Organic Synthesis, Chap 4 Material organized (roughly) by transformation From March, 1992, p1208 H H Two general classes: Transition metal hydrogenation and dissolving metal reduction Hydrogenation: Covered in much more detail in Advanced Synthesis and Catalysis. H HM H2 General trends: more substituted = slower relationship of pressure:rate often not simple