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Chen Lab is broadly interested in mechanisms of signal transduction, namely how a cell communicates with its surroundings and within itself.

1 Joseph Martin Ready Department of Biochemistry University of Texas Southwestern Medical Center 5323 Harry Hines Blvd. Dallas, TX 75390-9038 (214) 648-0313 joseph.ready@utsouthwestern.edu Employment 2012 – Professor, UT Southwestern 2009 – Director, Medicinal Chemistry Laboratory, UT Southwestern 2007 – 2012 Associate Professor, UT Southwestern 2007 – Chair, chemistry training track, UT Southwestern 2003 – 2007 Assistant Professor, UT Southwestern and

Eugene McDermott Center for Human Growth and Development Southwestern Medical School 5323 Harry Hines Blvd. / Dallas, Texas 75390-8591 (214) 648-1695 Fax (214) 648-1666 Email: chao.xing@utsouthwestern.edu Computational Biologist I The laboratories of Dr. Ralph DeBerardinis at Children’s Research Institute (https://cri.utsw.edu/scientists/ralph-deberardinis-laboratory/) and Dr. Chao Xing at McDermott Center for Human Growth and Development (https://labs.utsouthwestern.edu

Please contact Dr. Ralph Mason at ralph.mason@utsouthwestern.edu for more information. DATE SPEAKER TITLE LOCATION Friday, November 22, 2019 Rathan Subramaniam, MD, PhD, MPH Professor of Radiology Chief, Division of Nuclear Medicine UT Southwestern “Neuroendocrine Tumor and Prostate Cancer Theranosis – UT Southwestern Experience” K2.610 Friday, January 24, 2020 Brian W. Pogue, PhD MacLean Professor Engineering Science Director of MS Meg

Chen Lab Journal Club The Last Friday of every month, 4:20PM at NA6 small conference room. Date 09.15. Mingjian 10.15. Haocheng 11.15. Seoyun 01.16. Peiqing 02.16. Hui Y. 03.16. Conggang 04.16. Youtong 05.16. Daxing 06.16. Philip 07.16. Tuo 08.16. Hua

December 26, 2016 Chen Lab Weekly Meeting Schedule Wednesday at 9 am (unless indicated otherwise), NA6.214 1/4/17 Chee-Kwee & Jueqi 1/19/17 (Thursday) Mingjian & Shuiqing (NA8.218) 1/24/17 (Tuesday) Junyao & Seoyun (NA8.218) 2/3/17 (Friday) Youtong & Fenghe 2/8/17 Nicole & Philip 2/15/17 Xiang G & Xiang C 2/24/17 (Friday) Ming & Hanze W 3/1/17 Conggang & Hua 3/8/17 Peiqing & Hui Y 3/15/17 Xiaojun & Junjiao 3/24/17 (Friday

1 FRDA fibroblasts Short alleles <499 repeats Medium alleles 500 – 999 repeats Long alleles >1000 repeats B - indicates line established from a second, independent skin biopsy of the same individual Cell Line Sex Sampling Age Age of Onset GAA repeats Allele 1 Allele 2 4 M 30 11 597 848 21 M 35 8 622 738 50 M 33 13 353 616 66 M 70 41 110 590 68 F 21 7 570 1200 86 F 30 18 367 780 88 F 50 16 520 520 90 F 29 7 556 556 90B F 33 7 570 570 130 M 56 41

Postdoctoral Position in Neuroimaging A postdoctoral training position is available in the BioMedical Imaging Research Lab (BiMIR) led by Dr. Jiaen Liu in the Advanced Imaging Research Center (AIRC) at UT Southwestern Medical Center to develop advanced high resolution MRI methods for neuroimaging applications. BiMIR has several exciting projects related to novel MRI acquisition and reconstruction, ultrahigh-field MRI (≥7 T), quantitative MRI (T2, T2* and MT) for myelin and iron

Bu cc al B ru sh Gentra Puregene Handbook 06/201128 Protocol: DNA Purification from a Buccal Brush Using the Gentra Puregene Buccal Cell Kit This protocol is for purification of genomic DNA from 1 buccal brush using the Gentra Puregene Buccal Cell Kit. Things to do before starting � Preheat water baths to 55°C for use in step 3b and 65°C for use in steps 3a and 17 of the procedure. � Optional: Preheat water bath to 37°C for use in step 5 of the procedure. Procedure 1. To collect