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UT Southwestern researchers have discovered a new form of progeria, a rare premature-aging syndrome, in a man from Malaysia and traced its cause to a novel gene mutation.

Treating complex bacterial infections with customized therapies tailored to the infection and the patient is closer to reality, thanks to researchers at UT Southwestern Medical Center.

Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.

With flu cases on the rise, geriatric specialists at UT Southwestern Medical Center say vaccinations are particularly important this year for people 65 and older who are more at risk from complications than other age groups.

When McKinney real estate developer John Hill was 35, his father died of prostate cancer. The elder Mr. Hill had undergone surgery to remove his prostate a few years earlier, but the cancer had already spread.

Patients who develop lupus as children will eventually shift to adult rheumatology care. In a unique collaboration between rheumatologists at UT Southwestern and Children’s Health, investigators conducted a qualitative study, which showed that patients’ health literacy and taking an active role in their own care are important to successful transitions.

A clinical trial is only as powerful as its participants. For years, researchers have struggled to fill clinical trials and enroll sufficiently diverse groups of patients for results to reflect the broader population, in part because of stringent guidelines on who can participate.

A single mutation in a gene, Kcnc3, which encodes a potassium channel in neurons, causes learning deficits in mice, UT Southwestern researchers report in a new study in PNAS.

UT Southwestern will lead a multisite initiative funded by the National Cancer Institute (NCI) to identify biomarkers to improve risk assessment and early detection of hepatocellular cancer (HCC), the most common form of liver cancer, among patients with cirrhosis.

Building upon previous work at UT Southwestern Medical Center, investigators report the results of a clinical trial exploring the role of stereotactic ablative radiation therapy (SAbR) for patients with a handful of metastases, or so-called oligometastatic disease.