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A weekly dose of semaglutide (Ozempic, Wegovy) significantly reduced the risk of major adverse cardiovascular events (MACEs) in people who are overweight or obese with cardiovascular disease but no diabetes regardless of blood sugar level, according to a clinical trial including researchers from UT Southwestern Medical Center.

Mysterious cells that secrete hormones in the large intestine play a key role in regulating body weight through their relationship with intestinal bacteria, a study led by UT Southwestern Medical Center researchers suggests. Their findings, published in Nature Metabolism, could lead to new treatments for obesity and extreme weight loss.

The scorching heat can be inescapable this time of year, and as temperatures hover around triple digits, experts at UT Southwestern Medical Center caution that uncomfortable weather can escalate to dangerous health conditions.

A computer model developed by UT Southwestern Medical Center researchers significantly enhances the ability of scientists to detect communication between cells according to a new study published in Nature Methods.

Patients with a common movement disorder known as essential tremor (ET) developed dementia at three times the rate of similarly aged people in the general population, a study led by UT Southwestern Medical Center researchers shows.

Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors, UT Southwestern Medical Center researchers showed in a new study.

Patients who are younger than about 40, male, or Black are among those most at risk for revision surgery after having had a total knee replacement, according to researchers at UT Southwestern Medical Center.

– An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world’s most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.

Women who take oral contraceptives may be significantly less likely to experience certain musculoskeletal injuries than women who do not take the drugs or men, according to a study by UT Southwestern Medical Center.

UT Southwestern Medical Center researchers have developed an artificial intelligence (AI) method that writes its own algorithms and may one day operate as an “automated scientist” to extract the meaning behind complex datasets.